MSH6, mutS homolog 6, 2956
N. diseases: 296; N. variants: 642
Source: ALL
| Variant | Gene | Disease | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||||
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0.700 | GeneticVariation | UNIPROT | Mutation analysis of the MLH1, MSH2 and MSH6 genes in patients with double primary cancers of the colorectum and the endometrium: a population-based study in northern Sweden. | 14961575 | 2004 | |||||||
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0.700 | GeneticVariation | UNIPROT | Mutation analysis of the MLH1, MSH2 and MSH6 genes in patients with double primary cancers of the colorectum and the endometrium: a population-based study in northern Sweden. | 14961575 | 2004 | |||||||
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0.700 | GeneticVariation | UNIPROT | Mutation analysis of the MLH1, MSH2 and MSH6 genes in patients with double primary cancers of the colorectum and the endometrium: a population-based study in northern Sweden. | 14961575 | 2004 | |||||||
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0.700 | GeneticVariation | UNIPROT | Do MSH6 mutations contribute to double primary cancers of the colorectum and endometrium? | 11153917 | 2000 | |||||||
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0.700 | GeneticVariation | UNIPROT | Do MSH6 mutations contribute to double primary cancers of the colorectum and endometrium? | 11153917 | 2000 | |||||||
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0.700 | GeneticVariation | UNIPROT | Do MSH6 mutations contribute to double primary cancers of the colorectum and endometrium? | 11153917 | 2000 | |||||||
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T | 0.700 | CausalMutation | CLINVAR | |||||||||
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T | 0.700 | CausalMutation | CLINVAR | |||||||||
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0.700 | GeneticVariation | UNIPROT | ||||||||||
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T | 0.700 | CausalMutation | CLINVAR | |||||||||
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T | 0.700 | CausalMutation | CLINVAR | |||||||||
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T | 0.700 | CausalMutation | CLINVAR | |||||||||
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T | 0.700 | GeneticVariation | CLINVAR | |||||||||
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0.010 | GeneticVariation | BEFREE | To the best of our knowledge, this is the first description of MSH6 T767I pathogenic variant that could be associated with a hereditary endometrial cancer. | 31100584 | 2019 | |||||||
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0.010 | GeneticVariation | BEFREE | Unselected Jewish women with EC who were diagnosed from January 1982 to January 2008 were genotyped for the predominant mutations in Jewish individuals in BRCA1 (185delAG, 5382InsC, Tyr978X) BRCA2 (6174delT), MSH2 (A636P, 324delCA) and MSH6 (c.3984_3987dup). | 20850175 | 2010 |