SENP1, SUMO specific peptidase 1, 29843

N. diseases: 79; N. variants: 5
Disease: Breast Carcinoma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs61918808
rs61918808
Entrez Id: 29843
Gene Symbol: SENP1
SENP1
CUI: C0678222
Disease:
Breast Carcinoma 		0.010 GeneticVariation BEFREE Among the patients who received neoadjuvant chemotherapy, T allele and TT genotype of SENP1 rs61918808 were less likely to achieve pCR (P < .05).We first reported SENPs variants were not associated with BC risk in Chinese population, but presented specific effect on clinicopathological features of BC. 30732133 2019
dbSNP: rs12297820
rs12297820
Entrez Id: 29843
Gene Symbol: SENP1
SENP1
CUI: C0678222
Disease:
Breast Carcinoma 		0.010 GeneticVariation BEFREE The aim of these studies was to investigate an association between polymorphic variants (SNPs) of the SENP1 gene (c.1691 + 36C > T, rs12297820) and SENP2 gene (c.902C > A, p.Thr301Lys, rs6762208) and a risk of breast cancer occurrence. 27178176 2016