|
rs1042140
|
HLA-DPA1;HLA-DPB1
|
BERYLLIUM DISEASE, CHRONIC, SUSCEPTIBILITY TO
|
G |
0.700 |
SusceptibilityMutation |
CLINVAR |
|
|
|
|
rs1042140
|
HLA-DPA1;HLA-DPB1
|
Deuteranomaly
|
|
0.010 |
GeneticVariation |
BEFREE |
One described Human Leukocyte Antigen gene variant, HLA-DP beta 1*0201, contains a substitution of glutamate for lysine at position 69 that appears to have high sensitivity (approximately 94%) but low specificity (approximately 70%) with respect to CBD among individuals occupationally exposed to respirable beryllium.
|
10795342 |
2000 |
|
rs1367728
|
HLA-DPA1
|
Diabetes Mellitus, Insulin-Dependent
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.
|
17632545 |
2007 |
|
rs3077
|
HLA-DPA1
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation |
GWASDB |
TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.
|
17804836 |
2007 |
|
rs987870
|
HLA-DPA1;HLA-DPB1
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation |
GWASDB |
TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.
|
17804836 |
2007 |
|
rs3077
|
HLA-DPA1
|
Hepatitis B
|
|
0.900 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians.
|
19349983 |
2009 |
|
rs3135021
|
HLA-DPA1;HLA-DPB1
|
Hepatitis B
|
|
0.710 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians.
|
19349983 |
2009 |
|
rs2301220
|
HLA-DPA1
|
Hepatitis B
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians.
|
19349983 |
2009 |
|
rs9277341
|
HLA-DPA1
|
Hepatitis B
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians.
|
19349983 |
2009 |
|
rs3077
|
HLA-DPA1
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation |
GWASDB |
REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.
|
19503088 |
2009 |
|
rs9277341
|
HLA-DPA1
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation |
GWASDB |
REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.
|
19503088 |
2009 |
|
rs987870
|
HLA-DPA1;HLA-DPB1
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation |
GWASDB |
REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.
|
19503088 |
2009 |
|
rs1431403
|
HLA-DPA1;HLA-DPB1
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.
|
21156761 |
2011 |
|
rs9277359
|
HLA-DPA1;HLA-DPB1
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.
|
21156761 |
2011 |
|
rs9277377
|
HLA-DPA1;HLA-DPB1
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.
|
21156761 |
2011 |
|
rs9277378
|
HLA-DPA1;HLA-DPB1
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.
|
21156761 |
2011 |
|
rs928976
|
HLA-DPA1;HLA-DPB1
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.
|
21156761 |
2011 |
|
rs3077
|
HLA-DPA1
|
Hepatitis B, Chronic
|
|
0.760 |
GeneticVariation |
BEFREE |
A genome-wide association study identified single nucleotide polymorphisms (SNPs) rs3077 and rs9277535 located in the 3' untranslated regions of human leukocyte antigen (HLA) class II genes HLA-DPA1 and HLA-DPB1, respectively, as the independent variants most strongly associated with chronic hepatitis B.
|
21346778 |
2011 |
|
rs3077
|
HLA-DPA1
|
Hepatitis B
|
|
0.900 |
GeneticVariation |
BEFREE |
HLA - DPA1 rs3077 T was strongly associated with decreased risk of chronic HBV infection (odds ratio, .62; P = .001), consistent with the previous report.
|
21402545 |
2011 |
|
rs3077
|
HLA-DPA1
|
Liver carcinoma
|
|
0.740 |
GeneticVariation |
BEFREE |
However, rs3077 was not associated with the development of cirrhosis or hepatocellular carcinoma.
|
21402545 |
2011 |
|
rs3077
|
HLA-DPA1
|
Cirrhosis
|
|
0.010 |
GeneticVariation |
BEFREE |
However, rs3077 was not associated with the development of cirrhosis or hepatocellular carcinoma.
|
21402545 |
2011 |
|
rs3077
|
HLA-DPA1
|
Liver Cirrhosis
|
|
0.010 |
GeneticVariation |
BEFREE |
However, rs3077 was not associated with the development of cirrhosis or hepatocellular carcinoma.
|
21402545 |
2011 |
|
rs3077
|
HLA-DPA1
|
Hepatitis B, Chronic
|
|
0.760 |
GeneticVariation |
BEFREE |
Chronic hepatitis B susceptibility loci in HLA-DP region (rs3077 and rs9277535) identified by genome-wide scan in Japanese population were validated in Chinese population.
|
21408128 |
2011 |
|
rs2071349
|
HLA-DPA1;HLA-DPB1
|
Lupus Erythematosus, Systemic
|
|
0.010 |
GeneticVariation |
BEFREE |
Conditional haplotype analysis revealed three other SNPs, rs204890 (OR = 1.86, p = 1.2 × 10(-4)), rs2071349 (OR = 1.53, p = 1.0 × 10(-3)), and rs2844580 (OR = 1.43, p = 1.3 × 10(-3)), to be associated with SLE independent of the rs9271366 SNP.
|
21695597 |
2011 |
|
rs3077
|
HLA-DPA1
|
Hepatitis B
|
G |
0.900 |
GeneticVariation |
GWASCAT |
A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population.
|
21750111 |
2011 |