HLA-DQA1, major histocompatibility complex, class II, DQ alpha 1, 3117
N. diseases: 427; N. variants: 101
Source: ALL
| Variant | Gene | Disease | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
|
A | 0.810 | GeneticVariation | GWASCAT | Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies. | 31036433 | 2019 | ||||||
|
|
|
A | 0.810 | GeneticVariation | GWASCAT | Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. | 29273806 | 2018 | ||||||
|
|
|
A | 0.810 | GeneticVariation | GWASCAT | Identification of a new locus at 16q12 associated with time to asthma onset. | 27130862 | 2016 | ||||||
|
|
|
0.810 | GeneticVariation | GWASCAT | Of these, a common polymorphism (rs9272346) localizing to within 1 Kb of HLA-DQA1 (chromosome 6p21.3) was associated with asthma in adults (P-value = 2.2E-08) with consistent evidence in the more heterogeneous group of adults and children (P-value = 1.0E-04). | 23181788 | 2012 | |||||||
|
|
|
0.810 | GeneticVariation | GWASDB | Of these, a common polymorphism (rs9272346) localizing to within 1 Kb of HLA-DQA1 (chromosome 6p21.3) was associated with asthma in adults (P-value = 2.2E-08) with consistent evidence in the more heterogeneous group of adults and children (P-value = 1.0E-04). | 23181788 | 2012 | |||||||
|
|
|
0.810 | GeneticVariation | BEFREE | Of these, a common polymorphism (rs9272346) localizing to within 1 Kb of HLA-DQA1 (chromosome 6p21.3) was associated with asthma in adults (P-value = 2.2E-08) with consistent evidence in the more heterogeneous group of adults and children (P-value = 1.0E-04). | 23181788 | 2012 | |||||||
|
|
|
0.800 | GeneticVariation | GWASCAT | Large-scale, multiethnic genome-wide association study identifies novel loci contributing to asthma susceptibility in adults. | 30578877 | 2019 | |||||||
|
|
|
0.800 | GeneticVariation | GWASDB | A large-scale, consortium-based genomewide association study of asthma. | 20860503 | 2010 | |||||||
|
|
|
A | 0.700 | GeneticVariation | GWASCAT | Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis. | 31619474 | 2019 | ||||||
|
|
|
T | 0.700 | GeneticVariation | GWASCAT | Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. | 30929738 | 2019 | ||||||
|
|
|
A | 0.700 | GeneticVariation | GWASCAT | Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. | 30929738 | 2019 | ||||||
|
|
|
A | 0.700 | GeneticVariation | GWASCAT | Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. | 30929738 | 2019 | ||||||
|
|
|
0.700 | GeneticVariation | GWASCAT | A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases. | 29785011 | 2018 | |||||||
|
|
|
0.700 | GeneticVariation | GWASCAT | Detection and interpretation of shared genetic influences on 42 human traits. | 27182965 | 2016 | |||||||
|
|
|
0.700 | GeneticVariation | GWASDB | Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia. | 21150878 | 2011 |