Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs13115636
rs13115636
Entrez Id: 323
Gene Symbol: APBB2
APBB2
CUI: C0596887
Disease:
mathematical ability 		T 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs13137594
rs13137594
Entrez Id: 323
Gene Symbol: APBB2
APBB2
CUI: C0596887
Disease:
mathematical ability 		A 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs34177316
rs34177316
Entrez Id: 323;107986273
Gene Symbol: APBB2;LOC107986273
APBB2;LOC107986273
CUI: C1269683
Disease:
Major Depressive Disorder 		0.700 GeneticVariation GWASCAT Analysis of 23andMe antidepressant efficacy survey data: implication of circadian rhythm and neuroplasticity in bupropion response. 27622933 2016
dbSNP: rs34177316
rs34177316
Entrez Id: 323;107986273
Gene Symbol: APBB2;LOC107986273
APBB2;LOC107986273
CUI: C0525045
Disease:
Mood Disorders 		0.700 GeneticVariation GWASCAT Analysis of 23andMe antidepressant efficacy survey data: implication of circadian rhythm and neuroplasticity in bupropion response. 27622933 2016
dbSNP: rs34177316
rs34177316
Entrez Id: 323;107986273
Gene Symbol: APBB2;LOC107986273
APBB2;LOC107986273
CUI: C0041696
Disease:
Unipolar Depression 		0.700 GeneticVariation GWASCAT Analysis of 23andMe antidepressant efficacy survey data: implication of circadian rhythm and neuroplasticity in bupropion response. 27622933 2016
dbSNP: rs59892895
rs59892895
Entrez Id: 323
Gene Symbol: APBB2
APBB2
CUI: C0339573
Disease:
Glaucoma, Primary Open Angle 		0.010 GeneticVariation BEFREE The GWAS discovery meta-analysis demonstrated association of variants at amyloid-β A4 precursor protein-binding family B member 2 (APBB2; chromosome 4, rs59892895T>C) with primary open-angle glaucoma (odds ratio [OR], 1.32 [95% CI, 1.20-1.46]; P = 2 × 10-8). 31688885 2019
dbSNP: rs13133980
rs13133980
Entrez Id: 323
Gene Symbol: APBB2
APBB2
CUI: C0338656
Disease:
Impaired cognition 		0.010 GeneticVariation BEFREE Also the hCV1558625-rs13133980 AG haplotype increased relative risk for severe cognitive impairment in centenarians. 23384821 2013