IRGM, immunity related GTPase M, 345611

N. diseases: 6; N. variants: 5
Disease: Crohn Disease ×
Source: GWASCAT ×
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1000113
rs1000113
Entrez Id: 345611
Gene Symbol: IRGM
IRGM
CUI: C0010346
Disease:
Crohn Disease 		T 0.840 GeneticVariation GWASCAT Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. 17554300 2007
dbSNP: rs11747270
rs11747270
Entrez Id: 345611
Gene Symbol: IRGM
IRGM
CUI: C0010346
Disease:
Crohn Disease 		G 0.820 GeneticVariation GWASCAT Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. 18587394 2008
dbSNP: rs7714584
rs7714584
Entrez Id: 345611
Gene Symbol: IRGM
IRGM
CUI: C0010346
Disease:
Crohn Disease 		G 0.800 GeneticVariation GWASCAT Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. 21102463 2010
dbSNP: rs11741861
rs11741861
Entrez Id: 91975;345611
Gene Symbol: ZNF300;IRGM
ZNF300;IRGM
CUI: C0010346
Disease:
Crohn Disease 		0.700 GeneticVariation GWASCAT Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. 28067908 2017
dbSNP: rs11749391
rs11749391
Entrez Id: 345611
Gene Symbol: IRGM
IRGM
CUI: C0010346
Disease:
Crohn Disease 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
dbSNP: rs11741861
rs11741861
Entrez Id: 91975;345611
Gene Symbol: ZNF300;IRGM
ZNF300;IRGM
CUI: C0010346
Disease:
Crohn Disease 		G 0.700 GeneticVariation GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919 2015