APOC4, apolipoprotein C4, 346

N. diseases: 25; N. variants: 6
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12721109
rs12721109
Entrez Id: 346;100533990
Gene Symbol: APOC4;APOC4-APOC2
APOC4;APOC4-APOC2
CUI: C0202117
Disease:
Low density lipoprotein cholesterol measurement 		0.800 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584 2019
dbSNP: rs5167
rs5167
Entrez Id: 344;346;100533990
Gene Symbol: APOC2;APOC4;APOC4-APOC2
APOC2;APOC4;APOC4-APOC2
CUI: C0392885
Disease:
High density lipoprotein measurement 		0.800 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584 2019
dbSNP: rs12721109
rs12721109
Entrez Id: 346;100533990
Gene Symbol: APOC4;APOC4-APOC2
APOC4;APOC4-APOC2
CUI: C1445957
Disease:
Serum total cholesterol measurement 		G 0.800 GeneticVariation GWASCAT A large electronic-health-record-based genome-wide study of serum lipids. 29507422 2018
dbSNP: rs12721109
rs12721109
Entrez Id: 346;100533990
Gene Symbol: APOC4;APOC4-APOC2
APOC4;APOC4-APOC2
CUI: C0202117
Disease:
Low density lipoprotein cholesterol measurement 		G 0.800 GeneticVariation GWASCAT A large electronic-health-record-based genome-wide study of serum lipids. 29507422 2018
dbSNP: rs5167
rs5167
Entrez Id: 344;346;100533990
Gene Symbol: APOC2;APOC4;APOC4-APOC2
APOC2;APOC4;APOC4-APOC2
CUI: C0392885
Disease:
High density lipoprotein measurement 		T 0.800 GeneticVariation GWASCAT A large electronic-health-record-based genome-wide study of serum lipids. 29507422 2018
dbSNP: rs5167
rs5167
Entrez Id: 344;346;100533990
Gene Symbol: APOC2;APOC4;APOC4-APOC2
APOC2;APOC4;APOC4-APOC2
CUI: C0392885
Disease:
High density lipoprotein measurement 		0.800 GeneticVariation GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010 2018
dbSNP: rs12721109
rs12721109
Entrez Id: 346;100533990
Gene Symbol: APOC4;APOC4-APOC2
APOC4;APOC4-APOC2
CUI: C0202117
Disease:
Low density lipoprotein cholesterol measurement 		0.800 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs12721109
rs12721109
Entrez Id: 346;100533990
Gene Symbol: APOC4;APOC4-APOC2
APOC4;APOC4-APOC2
CUI: C0202117
Disease:
Low density lipoprotein cholesterol measurement 		0.800 GeneticVariation GWASDB Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project. 22629316 2012
dbSNP: rs12721109
rs12721109
Entrez Id: 346;100533990
Gene Symbol: APOC4;APOC4-APOC2
APOC4;APOC4-APOC2
CUI: C1445957
Disease:
Serum total cholesterol measurement 		0.800 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs5167
rs5167
Entrez Id: 344;346;100533990
Gene Symbol: APOC2;APOC4;APOC4-APOC2
APOC2;APOC4;APOC4-APOC2
CUI: C0392885
Disease:
High density lipoprotein measurement 		0.800 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs12721109
rs12721109
Entrez Id: 346;100533990
Gene Symbol: APOC4;APOC4-APOC2
APOC4;APOC4-APOC2
CUI: C0002395
Disease:
Alzheimer's Disease 		0.700 GeneticVariation GWASCAT GWAS on family history of Alzheimer's disease. 29777097 2018
dbSNP: rs5167
rs5167
Entrez Id: 344;346;100533990
Gene Symbol: APOC2;APOC4;APOC4-APOC2
APOC2;APOC4;APOC4-APOC2
CUI: C2985280
Disease:
Blood Protein Measurement 		G 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488 2018
dbSNP: rs5167
rs5167
Entrez Id: 344;346;100533990
Gene Symbol: APOC2;APOC4;APOC4-APOC2
APOC2;APOC4;APOC4-APOC2
CUI: C0202236
Disease:
Triglycerides measurement 		T 0.700 GeneticVariation GWASCAT A large electronic-health-record-based genome-wide study of serum lipids. 29507422 2018
dbSNP: rs79429216
rs79429216
Entrez Id: 346;100533990
Gene Symbol: APOC4;APOC4-APOC2
APOC4;APOC4-APOC2
CUI: C2985280
Disease:
Blood Protein Measurement 		A 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488 2018
dbSNP: rs5167
rs5167
Entrez Id: 344;346;100533990
Gene Symbol: APOC2;APOC4;APOC4-APOC2
APOC2;APOC4;APOC4-APOC2
CUI: C2825895
Disease:
Granulocyte Colony Stimulating Factor Measurement 		G 0.700 GeneticVariation GWASCAT Connecting genetic risk to disease end points through the human blood plasma proteome. 28240269 2017
dbSNP: rs12721109
rs12721109
Entrez Id: 346;100533990
Gene Symbol: APOC4;APOC4-APOC2
APOC4;APOC4-APOC2
CUI: C0428474
Disease:
Serum LDL cholesterol measurement 		0.700 GeneticVariation GWASDB Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project. 22629316 2012
dbSNP: rs12721109
rs12721109
Entrez Id: 346;100533990
Gene Symbol: APOC4;APOC4-APOC2
APOC4;APOC4-APOC2
CUI: C0428474
Disease:
Serum LDL cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs2288912
rs2288912
Entrez Id: 344;346;100533990
Gene Symbol: APOC2;APOC4;APOC4-APOC2
APOC2;APOC4;APOC4-APOC2
CUI: C0428472
Disease:
Serum HDL cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs2288912
rs2288912
Entrez Id: 344;346;100533990
Gene Symbol: APOC2;APOC4;APOC4-APOC2
APOC2;APOC4;APOC4-APOC2
CUI: C0392885
Disease:
High density lipoprotein measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs5157
rs5157
Entrez Id: 346;100533990
Gene Symbol: APOC4;APOC4-APOC2
APOC4;APOC4-APOC2
CUI: C0392885
Disease:
High density lipoprotein measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs5157
rs5157
Entrez Id: 346;100533990
Gene Symbol: APOC4;APOC4-APOC2
APOC4;APOC4-APOC2
CUI: C0428472
Disease:
Serum HDL cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs5167
rs5167
Entrez Id: 344;346;100533990
Gene Symbol: APOC2;APOC4;APOC4-APOC2
APOC2;APOC4;APOC4-APOC2
CUI: C0428472
Disease:
Serum HDL cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs12721109
rs12721109
Entrez Id: 346;100533990
Gene Symbol: APOC4;APOC4-APOC2
APOC4;APOC4-APOC2
CUI: C1168443
Disease:
Pseudocholinesterase Measurement 		0.700 GeneticVariation GWASDB Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits. 21943158 2011
dbSNP: rs5167
rs5167
Entrez Id: 344;346;100533990
Gene Symbol: APOC2;APOC4;APOC4-APOC2
APOC2;APOC4;APOC4-APOC2
CUI: C1272321
Disease:
Autoantibody measurement 		0.700 GeneticVariation GWASDB Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia. 19734900 2009
dbSNP: rs1132899
rs1132899
Entrez Id: 344;346;100533990
Gene Symbol: APOC2;APOC4;APOC4-APOC2
APOC2;APOC4;APOC4-APOC2
CUI: C1956346
Disease:
Coronary Artery Disease 		0.010 GeneticVariation BEFREE Our data provides the first evidence that APOC4 rs1132899 polymorphism was associated with an increased risk of premature CAD in Chinese subjects, and the association was more significant among male subjects. 26129832 2015