|
rs20541
|
IL13;TH2LCRR
|
Allergic rhinitis (disorder)
|
|
0.070 |
GeneticVariation |
BEFREE |
Our findings suggest that IL-13 SNP rs20541 is significantly associated with AR risk in Asians but not in Caucasians.
|
29687183 |
2018 |
|
rs20541
|
IL13;TH2LCRR
|
Allergic rhinitis (disorder)
|
|
0.070 |
GeneticVariation |
BEFREE |
Our aim was to observe factors associated with IL13 rs20541 polymorphism and other factors with or without allergic comorbidities such as subject-reported allergic rhinitis (AR) and/or allergic conjunctivitis (AC) symptoms in adult asthmatics.
|
28273659 |
2017 |
|
rs20541
|
IL13;TH2LCRR
|
Allergic rhinitis (disorder)
|
|
0.070 |
GeneticVariation |
BEFREE |
Gene-environment interactions between IL-13 (rs20541) and antibiotics or mold may play a role in AR.
|
24973272 |
2014 |
|
rs20541
|
IL13;TH2LCRR
|
Allergic rhinitis (disorder)
|
|
0.070 |
GeneticVariation |
BEFREE |
Association of interleukin-13 SNP rs20541 (Arg>Gln) to allergic rhinitis in an Asian population of ethnic Chinese in Singapore.
|
23954258 |
2013 |
|
rs20541
|
IL13;TH2LCRR
|
Allergic rhinitis (disorder)
|
|
0.070 |
GeneticVariation |
BEFREE |
When stratifying for race, IL-13 SNP rs20541 exhibited increased AR risk in Asians (Gln versus Arg: OR=1.20, 95% CI=1.06-1.36; Gln/Gln versus Arg/Arg: OR=1.57, 95% CI=1.17-2.12; Arg/Gln+Gln/Gln versus Arg/Arg: OR=1.22, 95% CI=1.04-1.44; Gln/Gln versus Arg/Gln+Arg/Arg: OR=1.45, 95% CI=1.09-1.93), while no significant association was detected in Caucasians (Gln versus Arg: OR=1.28, 95% CI=0.93~1.78; Gln/Gln versus Arg/Arg: OR=1.42, 95% CI=0.96-2.11; Arg/Gln+Gln/Gln versus Arg/Arg: OR=1.35, 95% CI=0.89-2.05; Gln/Gln versus Arg/Gln+Arg/Arg: OR=1.37, 95% CI=0.93-2.02).
|
23545317 |
2013 |
|
rs20541
|
IL13;TH2LCRR
|
Allergic rhinitis (disorder)
|
|
0.070 |
GeneticVariation |
BEFREE |
However, a recent meta-analysis using data from these 6 studies has shown that the A allele of IL13 SNP rs20541 was associated with an increased risk of allergic rhinitis, whereas no such relationship existed between IL13 SNP rs1800925 and allergic rhinitis.
|
22023794 |
2011 |
|
rs20541
|
IL13;TH2LCRR
|
Allergic rhinitis (disorder)
|
|
0.070 |
GeneticVariation |
BEFREE |
We conclude that there is evidence for an overall association between IL13 SNP rs20541 and increased risk of AR, especially in mixed-age populations.
|
21309855 |
2011 |
|
rs1800925
|
IL13;TH2LCRR
|
Allergic rhinitis (disorder)
|
|
0.050 |
GeneticVariation |
BEFREE |
However, the accumulating evidence does not support an association of IL-13 SNP rs1800925 and CD14 SNP rs2569190 with AR risk.
|
29687183 |
2018 |
|
rs1800925
|
IL13;TH2LCRR
|
Allergic rhinitis (disorder)
|
|
0.050 |
GeneticVariation |
BEFREE |
The aim of the present study was to conduct a meta-analysis assessing the possible association of IL-13 SNP rs1800925 with allergic rhinitis risk.
|
22750299 |
2012 |
|
rs1800925
|
IL13;TH2LCRR
|
Allergic rhinitis (disorder)
|
|
0.050 |
GeneticVariation |
BEFREE |
However, a recent meta-analysis using data from these 6 studies has shown that the A allele of IL13 SNP rs20541 was associated with an increased risk of allergic rhinitis, whereas no such relationship existed between IL13 SNP rs1800925 and allergic rhinitis.
|
22023794 |
2011 |
|
rs1800925
|
IL13;TH2LCRR
|
Allergic rhinitis (disorder)
|
|
0.050 |
GeneticVariation |
BEFREE |
IL13 SNP rs1800925 and IL4R SNP 1801275 did not demonstrate overall associations with AR.
|
21309855 |
2011 |
|
rs1800925
|
IL13;TH2LCRR
|
Allergic rhinitis (disorder)
|
|
0.050 |
GeneticVariation |
BEFREE |
A model with rs1058240, rs379568, and rs4143094 (GATA3) and rs1800925 (IL13) and their interactions was selected to predict rhinitis and positive SPT responses. rs1058240 was associated with rhinitis and allergic rhinitis (P < .05), and the gene-gene interaction rs1058240:rs1800925 was associated with rhinitis (P = .043).
|
18037162 |
2008 |