INCENP, inner centromere protein, 3619

N. diseases: 24; N. variants: 4
Disease: Breast Carcinoma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs7937840
rs7937840
Entrez Id: 3619
Gene Symbol: INCENP
INCENP
CUI: C0678222
Disease:
Breast Carcinoma 		T 0.700 GeneticVariation GWASCAT Association analysis identifies 65 new breast cancer risk loci. 29059683 2017
dbSNP: rs1675126
rs1675126
Entrez Id: 3619
Gene Symbol: INCENP
INCENP
CUI: C0678222
Disease:
Breast Carcinoma 		0.010 GeneticVariation BEFREE The synonymous SNP rs1675126 in exon 7 of INCENP was associated with overall breast cancer risk [per A allele odds ratio (OR) 0.95, 95% confidence interval (CI) 0.92-0.98, P = 0.007] and particularly with estrogen receptor (ER)-negative breast tumors (per A allele OR 0.89, 95% CI 0.83-0.95, P = 0.0005). 25586992 2015