IDO1, indoleamine 2,3-dioxygenase 1, 3620

N. diseases: 295; N. variants: 7
Disease: Depressive disorder ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs9657182
rs9657182
Entrez Id: 3620
Gene Symbol: IDO1
IDO1
CUI: C0011581
Disease:
Depressive disorder 		0.010 GeneticVariation BEFREE In subjects homozygous for the risk allele (CC, n=150), the odds ratio for developing moderate or severe depressive symptoms at treatment week 12 was 2.91 (confidence interval: 1.48-5.73) compared with TT homozygotes (n=270). rs9657182 did not predict depression in African Americans, who exhibited a markedly lower frequency of the risk allele at this locus. 21691274 2012