IRF4, interferon regulatory factor 4, 3662

N. diseases: 203; N. variants: 10
Disease: Experimental Organism Basal Cell Carcinoma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12203592
rs12203592
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C3811653
Disease:
Experimental Organism Basal Cell Carcinoma 		0.020 GeneticVariation BEFREE The significance of variation within the MC1R gene was confirmed and, in addition, position rs12203592 within the IRF4 gene was shown to be associated with BCC. 22512251 2012
dbSNP: rs12203592
rs12203592
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C3811653
Disease:
Experimental Organism Basal Cell Carcinoma 		0.020 GeneticVariation BEFREE Along with two known pigmentation loci, MC1R and OCA2, the IRF4 rs12203592 T allele was associated with an increased risk of each type of skin cancer (P value, 6.6 × 10(-4) for melanoma, 7.0 × 10(-7) for SCC, and 0.04 for BCC). 21270109 2011