ISL1, ISL LIM homeobox 1, 3670

N. diseases: 94; N. variants: 2
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1017
rs1017
Entrez Id: 3670
Gene Symbol: ISL1
ISL1
CUI: C0010068
Disease:
Coronary heart disease 		0.030 GeneticVariation BEFREE We concluded that rs1017 contributed to the risk of CHD in Chinese Han people, and ISL1 may be involved in the formation and development of the heart. 24634231 2014
dbSNP: rs1017
rs1017
Entrez Id: 3670
Gene Symbol: ISL1
ISL1
CUI: C0010068
Disease:
Coronary heart disease 		0.030 GeneticVariation BEFREE In conclusion, ISL1 common variant rs1017 is not associated with increased genetic risk of CHD in the white population. 23229290 2013
dbSNP: rs1017
rs1017
Entrez Id: 3670
Gene Symbol: ISL1
ISL1
CUI: C0010068
Disease:
Coronary heart disease 		0.030 GeneticVariation BEFREE This is the first study which indicates that ISL1 common variant rs1017 may not play a role in sporadic CHD susceptibility in the Chinese population. 22480195 2012
dbSNP: rs1017
rs1017
Entrez Id: 3670
Gene Symbol: ISL1
ISL1
CUI: C0152021
Disease:
Congenital heart disease 		0.020 GeneticVariation BEFREE Lack of association of the 3'-UTR polymorphism (rs1017) in the ISL1 gene and risk of congenital heart disease in the white population. 23229290 2013
dbSNP: rs1017
rs1017
Entrez Id: 3670
Gene Symbol: ISL1
ISL1
CUI: C0152021
Disease:
Congenital heart disease 		0.020 GeneticVariation BEFREE ISL1 common variant rs1017 is not associated with susceptibility to congenital heart disease in a Chinese population. 22480195 2012
dbSNP: rs3762977
rs3762977
Entrez Id: 3670;642366
Gene Symbol: ISL1;LOC642366
ISL1;LOC642366
CUI: C0018818
Disease:
Ventricular Septal Defects 		0.010 GeneticVariation BEFREE Carriers of the GG genotype of rs3762977 and the TT genotype of IVS+17C>T were less likely to have VSD, whereas variants in rs1701 did not affect the VSD risk. 23572340 2013