KDR, kinase insert domain receptor, 3791

N. diseases: 623; N. variants: 23
Disease: Hemangiosarcoma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs56302315
rs56302315
Entrez Id: 3791
Gene Symbol: KDR
KDR
CUI: C0018923
Disease:
Hemangiosarcoma 		0.010 GeneticVariation BEFREE Likewise, activating mutations in the receptor tyrosine kinase KDR (VEGFR2) have been reported in angiosarcomas and non-small cell lung cancers; the KDR A1065T mutation is reported to be sensitive to VEGFR kinase inhibitors, and fibroblast growth factor receptor inhibitors are in trials. 25679062 2015