Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1635
rs1635
Entrez Id: 222698;387032
Gene Symbol: NKAPL;ZKSCAN4
NKAPL;ZKSCAN4
CUI: C0036341
Disease:
Schizophrenia 		0.830 GeneticVariation BEFREE We detected a positive association of rs1635 with SZ, with the major allele (G) of rs1635 conferring a risk for SZ (P=0.033, OR=1.14). 26297123 2015
dbSNP: rs1635
rs1635
Entrez Id: 222698;387032
Gene Symbol: NKAPL;ZKSCAN4
NKAPL;ZKSCAN4
CUI: C0036341
Disease:
Schizophrenia 		0.830 GeneticVariation BEFREE This study suggested that rs1635 in the NKAPL gene appeared to play a role in conferring susceptibility to schizophrenia. 24972756 2014
dbSNP: rs1635
rs1635
Entrez Id: 222698;387032
Gene Symbol: NKAPL;ZKSCAN4
NKAPL;ZKSCAN4
CUI: C0036341
Disease:
Schizophrenia 		0.830 GeneticVariation GWASCAT We identified two susceptibility loci for schizophrenia at 6p21-p22.1 (rs1233710 in an intron of ZKSCAN4, P(combined) = 4.76 × 10(-11), odds ratio (OR) = 0.79; rs1635 in an exon of NKAPL, P(combined) = 6.91 × 10(-12), OR = 0.78; rs2142731 in an intron of PGBD1, P(combined) = 5.14 × 10(-10), OR = 0.79) and 11p11.2 (rs11038167 near the 5' UTR of TSPAN18, P(combined) = 1.09 × 10(-11), OR = 1.29; rs11038172, P(combined) = 7.21 × 10(-10), OR = 1.25; rs835784, P(combined) = 2.73 × 10(-11), OR = 1.27). 22037552 2011
dbSNP: rs1635
rs1635
Entrez Id: 222698;387032
Gene Symbol: NKAPL;ZKSCAN4
NKAPL;ZKSCAN4
CUI: C0036341
Disease:
Schizophrenia 		0.830 GeneticVariation BEFREE We identified two susceptibility loci for schizophrenia at 6p21-p22.1 (rs1233710 in an intron of ZKSCAN4, P(combined) = 4.76 × 10(-11), odds ratio (OR) = 0.79; rs1635 in an exon of NKAPL, P(combined) = 6.91 × 10(-12), OR = 0.78; rs2142731 in an intron of PGBD1, P(combined) = 5.14 × 10(-10), OR = 0.79) and 11p11.2 (rs11038167 near the 5' UTR of TSPAN18, P(combined) = 1.09 × 10(-11), OR = 1.29; rs11038172, P(combined) = 7.21 × 10(-10), OR = 1.25; rs835784, P(combined) = 2.73 × 10(-11), OR = 1.27). 22037552 2011
dbSNP: rs1635
rs1635
Entrez Id: 222698;387032
Gene Symbol: NKAPL;ZKSCAN4
NKAPL;ZKSCAN4
CUI: C0036341
Disease:
Schizophrenia 		0.830 GeneticVariation GWASDB We identified two susceptibility loci for schizophrenia at 6p21-p22.1 (rs1233710 in an intron of ZKSCAN4, P(combined) = 4.76 × 10(-11), odds ratio (OR) = 0.79; rs1635 in an exon of NKAPL, P(combined) = 6.91 × 10(-12), OR = 0.78; rs2142731 in an intron of PGBD1, P(combined) = 5.14 × 10(-10), OR = 0.79) and 11p11.2 (rs11038167 near the 5' UTR of TSPAN18, P(combined) = 1.09 × 10(-11), OR = 1.29; rs11038172, P(combined) = 7.21 × 10(-10), OR = 1.25; rs835784, P(combined) = 2.73 × 10(-11), OR = 1.27). 22037552 2011
dbSNP: rs1233710
rs1233710
Entrez Id: 387032
Gene Symbol: ZKSCAN4
ZKSCAN4
CUI: C0036341
Disease:
Schizophrenia 		0.710 GeneticVariation BEFREE We identified two susceptibility loci for schizophrenia at 6p21-p22.1 (rs1233710 in an intron of ZKSCAN4, P(combined) = 4.76 × 10(-11), odds ratio (OR) = 0.79; rs1635 in an exon of NKAPL, P(combined) = 6.91 × 10(-12), OR = 0.78; rs2142731 in an intron of PGBD1, P(combined) = 5.14 × 10(-10), OR = 0.79) and 11p11.2 (rs11038167 near the 5' UTR of TSPAN18, P(combined) = 1.09 × 10(-11), OR = 1.29; rs11038172, P(combined) = 7.21 × 10(-10), OR = 1.25; rs835784, P(combined) = 2.73 × 10(-11), OR = 1.27). 22037552 2011
dbSNP: rs1233710
rs1233710
Entrez Id: 387032
Gene Symbol: ZKSCAN4
ZKSCAN4
CUI: C0036341
Disease:
Schizophrenia 		0.710 GeneticVariation GWASDB We identified two susceptibility loci for schizophrenia at 6p21-p22.1 (rs1233710 in an intron of ZKSCAN4, P(combined) = 4.76 × 10(-11), odds ratio (OR) = 0.79; rs1635 in an exon of NKAPL, P(combined) = 6.91 × 10(-12), OR = 0.78; rs2142731 in an intron of PGBD1, P(combined) = 5.14 × 10(-10), OR = 0.79) and 11p11.2 (rs11038167 near the 5' UTR of TSPAN18, P(combined) = 1.09 × 10(-11), OR = 1.29; rs11038172, P(combined) = 7.21 × 10(-10), OR = 1.25; rs835784, P(combined) = 2.73 × 10(-11), OR = 1.27). 22037552 2011
dbSNP: rs17720293
rs17720293
Entrez Id: 387032
Gene Symbol: ZKSCAN4
ZKSCAN4
CUI: C0036341
Disease:
Schizophrenia 		C 0.700 GeneticVariation GWASCAT Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect. 30285260 2019
dbSNP: rs967005
rs967005
Entrez Id: 387032
Gene Symbol: ZKSCAN4
ZKSCAN4
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		T 0.700 GeneticVariation GWASDB GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region. 24871463 2014
dbSNP: rs12000
rs12000
Entrez Id: 222698;387032
Gene Symbol: NKAPL;ZKSCAN4
NKAPL;ZKSCAN4
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.700 GeneticVariation GWASDB REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis. 19503088 2009
dbSNP: rs2235359
rs2235359
Entrez Id: 387032
Gene Symbol: ZKSCAN4
ZKSCAN4
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.700 GeneticVariation GWASDB REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis. 19503088 2009
dbSNP: rs1679709
rs1679709
Entrez Id: 222698;387032
Gene Symbol: NKAPL;ZKSCAN4
NKAPL;ZKSCAN4
CUI: C0024623
Disease:
Malignant neoplasm of stomach 		0.010 GeneticVariation BEFREE We also associated the variant rs1679709 at 6p22.1 with reduced risk for gastric cancer (odds ratio, 0.80; P = 1.17 × 10<sup>-13</sup>). 28246015 2017
dbSNP: rs1679709
rs1679709
Entrez Id: 222698;387032
Gene Symbol: NKAPL;ZKSCAN4
NKAPL;ZKSCAN4
CUI: C0699791
Disease:
Stomach Carcinoma 		0.010 GeneticVariation BEFREE We also associated the variant rs1679709 at 6p22.1 with reduced risk for gastric cancer (odds ratio, 0.80; P = 1.17 × 10<sup>-13</sup>). 28246015 2017
dbSNP: rs12000
rs12000
Entrez Id: 222698;387032
Gene Symbol: NKAPL;ZKSCAN4
NKAPL;ZKSCAN4
CUI: C0036341
Disease:
Schizophrenia 		0.010 GeneticVariation BEFREE The combined study revealed that rs12000 and rs1150722 were still strongly associated with schizophrenia (rs12000: allele G>A, P(combined) = 0.0019, OR = 0.81; rs1150722: allele G>A, P(combined) = 3.00E-04, OR = 0.61). 23437227 2013
dbSNP: rs2235359
rs2235359
Entrez Id: 387032
Gene Symbol: ZKSCAN4
ZKSCAN4
CUI: C0036341
Disease:
Schizophrenia 		0.010 GeneticVariation BEFREE Haplotype ATTGACGC, comprising these eight SNPs (rs2235359, rs2185955, rs12214383, rs12000, rs1150724, rs1150722, rs3800324, and rs1997660), was significantly associated with schizophrenia (P = 6.60E-05). 23437227 2013