LPL, lipoprotein lipase, 4023

N. diseases: 290; N. variants: 116
Disease: Metabolic Syndrome X ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs268
rs268
Entrez Id: 4023
Gene Symbol: LPL
LPL
CUI: C0524620
Disease:
Metabolic Syndrome X 		G 0.800 GeneticVariation GWASDB Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits. 22399527 2012
dbSNP: rs268
rs268
Entrez Id: 4023
Gene Symbol: LPL
LPL
CUI: C0524620
Disease:
Metabolic Syndrome X 		G 0.800 GeneticVariation GWASCAT Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits. 22399527 2012
dbSNP: rs295
rs295
Entrez Id: 4023
Gene Symbol: LPL
LPL
CUI: C0524620
Disease:
Metabolic Syndrome X 		A 0.800 GeneticVariation GWASDB A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium. 21386085 2011
dbSNP: rs295
rs295
Entrez Id: 4023
Gene Symbol: LPL
LPL
CUI: C0524620
Disease:
Metabolic Syndrome X 		A 0.800 GeneticVariation GWASCAT A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium. 21386085 2011
dbSNP: rs301
rs301
Entrez Id: 4023
Gene Symbol: LPL
LPL
CUI: C0524620
Disease:
Metabolic Syndrome X 		C 0.800 GeneticVariation GWASCAT A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium. 21386085 2011
dbSNP: rs301
rs301
Entrez Id: 4023
Gene Symbol: LPL
LPL
CUI: C0524620
Disease:
Metabolic Syndrome X 		C 0.800 GeneticVariation GWASDB A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium. 21386085 2011
dbSNP: rs263
rs263
Entrez Id: 4023
Gene Symbol: LPL
LPL
CUI: C0524620
Disease:
Metabolic Syndrome X 		0.700 GeneticVariation GWASCAT Multiple genotype-phenotype association study reveals intronic variant pair on SIDT2 associated with metabolic syndrome in a Korean population. 30382898 2018
dbSNP: rs271
rs271
Entrez Id: 4023
Gene Symbol: LPL
LPL
CUI: C0524620
Disease:
Metabolic Syndrome X 		0.700 GeneticVariation GWASCAT Multiple genotype-phenotype association study reveals intronic variant pair on SIDT2 associated with metabolic syndrome in a Korean population. 30382898 2018
dbSNP: rs328
rs328
Entrez Id: 4023
Gene Symbol: LPL
LPL
CUI: C0524620
Disease:
Metabolic Syndrome X 		0.020 GeneticVariation BEFREE Diets high in carbohydrate may not be appropriate for rs328 G carriers with the metabolic syndrome. 26420199 2015
dbSNP: rs328
rs328
Entrez Id: 4023
Gene Symbol: LPL
LPL
CUI: C0524620
Disease:
Metabolic Syndrome X 		0.020 GeneticVariation BEFREE We found an association with elevated glucose levels (odds ratio (OR) = 2.9; p = 0.013) in carrying the AA genotype of rs1884051 in the ESR1 gene compared with the GG genotype, and the CC genotype of rs328 in the LPL gene was associated with MetS compared to the CG or GG genotype (OR = 2.8; p = 0.04). 26370976 2015
dbSNP: rs965384857
rs965384857
Entrez Id: 4023
Gene Symbol: LPL
LPL
CUI: C0524620
Disease:
Metabolic Syndrome X 		0.010 GeneticVariation BEFREE The apolipoprotein A5 Q139X, lipoprotein lipase (LPL) Hinf I, human paraoxonase 1 (PON1) 192Arg/Gln, cholesteryl ester transfer protein (CETP) Taq1B, adiponectin 45T>G and leptin (LEP) 25CAG were genotyped by real-time polymerase chain reaction in participants with and without MetS. 30381540 2018