LTA, lymphotoxin alpha, 4049

N. diseases: 353; N. variants: 26
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1041981
rs1041981
Entrez Id: 4049;100287329
Gene Symbol: LTA;LOC100287329
LTA;LOC100287329
CUI: C0027051
Disease:
Myocardial Infarction
0.720 GeneticVariation BEFREE Minor homozygous genotypes of polymorphisms in BAT1 (rs2239527, -23C/G), NFKBIL1 (rs2071592, -63T/A) and LTA (rs1800683, -162G/A; rs909253, 252G/A; rs1041981, Thr26Asn) were associated with moderately protective effects against myocardial infarction (P </= 0.045). 17517687 2007
dbSNP: rs1041981
rs1041981
Entrez Id: 4049;100287329
Gene Symbol: LTA;LOC100287329
LTA;LOC100287329
CUI: C0027051
Disease:
Myocardial Infarction
0.720 GeneticVariation BEFREE A recent large-scale, genome-wide association study of single nucleotide polymorphisms showed a strong association between susceptibility to myocardial infarction and the Thr26Asn polymorphism in the lymphotoxin-alpha (LTA) gene. 15973460 2005
dbSNP: rs1041981
rs1041981
Entrez Id: 4049;100287329
Gene Symbol: LTA;LOC100287329
LTA;LOC100287329
CUI: C0027051
Disease:
Myocardial Infarction
A 0.720 SusceptibilityMutation CLINVAR
dbSNP: rs909253
rs909253
Entrez Id: 4049;100287329
Gene Symbol: LTA;LOC100287329
LTA;LOC100287329
CUI: C0027051
Disease:
Myocardial Infarction
G 0.700 SusceptibilityMutation CLINVAR
dbSNP: rs1800683
rs1800683
Entrez Id: 4049;100287329
Gene Symbol: LTA;LOC100287329
LTA;LOC100287329
CUI: C0027051
Disease:
Myocardial Infarction
0.010 GeneticVariation BEFREE Minor homozygous genotypes of polymorphisms in BAT1 (rs2239527, -23C/G), NFKBIL1 (rs2071592, -63T/A) and LTA (rs1800683, -162G/A; rs909253, 252G/A; rs1041981, Thr26Asn) were associated with moderately protective effects against myocardial infarction (P </= 0.045). 17517687 2007