|
rs767649
|
MIR155HG;MIR155
|
Large-artery atherosclerosis (embolus/thrombosis)
|
|
0.010 |
GeneticVariation |
BEFREE |
The <i>miR-155</i> rs767649 polymorphism does not seem to be a key determinant of IS risk, whereas the <i>AT1R</i> rs1492099 polymorphism is linked to reduced LAA-stroke risk, and the rs275653 AA genotype is potentially protective against SAO strokes.
|
31721599 |
2020 |
|
rs767649
|
MIR155HG;MIR155
|
Ischemic stroke
|
|
0.010 |
GeneticVariation |
BEFREE |
The <i>miR-155</i> rs767649 polymorphism does not seem to be a key determinant of IS risk, whereas the <i>AT1R</i> rs1492099 polymorphism is linked to reduced LAA-stroke risk, and the rs275653 AA genotype is potentially protective against SAO strokes.
|
31721599 |
2020 |
|
rs767649
|
MIR155HG;MIR155
|
Rheumatoid Arthritis
|
|
0.010 |
GeneticVariation |
BEFREE |
MiR-155 and IMA levels were significantly associated with the genotype distribution of miR-155 (rs767649) in patients with RA and were higher in patients with the TT genotype.
|
31009294 |
2019 |
|
rs767649
|
MIR155HG;MIR155
|
Diabetic Retinopathy
|
|
0.010 |
GeneticVariation |
BEFREE |
These findings support that the rs767649 polymorphism in the pre-MIR155 gene is associated with DR in T2DM and that the miR-155 plasma levels might be associated with T2DM.
|
31751306 |
2019 |
|
rs767649
|
MIR155HG;MIR155
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.010 |
GeneticVariation |
BEFREE |
These findings support that the rs767649 polymorphism in the pre-MIR155 gene is associated with DR in T2DM and that the miR-155 plasma levels might be associated with T2DM.
|
31751306 |
2019 |
|
rs767649
|
MIR155HG;MIR155
|
Intracranial Aneurysm
|
|
0.010 |
GeneticVariation |
BEFREE |
The results of this study showed that the SNP rs767649 in the promoter of miR-155 could reduce the transcription activity of miR-155, while poorly expressed miR-155 could increase the incidence of IA rupture by increasing the expression of MMP-2, especially in subjects carrying the TT genotype of SNP rs767649.
|
31338876 |
2019 |
|
rs767649
|
MIR155HG;MIR155
|
Multiple Sclerosis
|
|
0.010 |
GeneticVariation |
BEFREE |
This study was conducted to investigate the association between mir155 rs767649, mir196a2 rs11614913 and mir23a rs3745453 polymorphism and the risk of multiple sclerosis in the Iranian MS patients in Isfahan.
|
30518189 |
2018 |
|
rs767649
|
MIR155HG;MIR155
|
Diabetes Mellitus, Insulin-Dependent
|
|
0.010 |
GeneticVariation |
BEFREE |
MiR-146a rs2910164 and miR-155 rs767649 polymorphisms were associated with protection for T1DM.
|
28101643 |
2017 |
|
rs767649
|
MIR155HG;MIR155
|
Malignant neoplasm of lung
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs767649 polymorphism, locating in the promoter of miR-155, was recently reported to be able to alter transcriptional activity of miR-155 and relate to lung cancer risk.
|
27717891 |
2016 |
|
rs767649
|
MIR155HG;MIR155
|
cervical cancer
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, rs767649 might be a causal variant for CC susceptibility.
|
27717891 |
2016 |
|
rs767649
|
MIR155HG;MIR155
|
Carcinoma of lung
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs767649 polymorphism, locating in the promoter of miR-155, was recently reported to be able to alter transcriptional activity of miR-155 and relate to lung cancer risk.
|
27717891 |
2016 |
|
rs767649
|
MIR155HG;MIR155
|
Primary malignant neoplasm of lung
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs767649 polymorphism, locating in the promoter of miR-155, was recently reported to be able to alter transcriptional activity of miR-155 and relate to lung cancer risk.
|
27717891 |
2016 |
|
rs767649
|
MIR155HG;MIR155
|
Malignant tumor of cervix
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, rs767649 might be a causal variant for CC susceptibility.
|
27717891 |
2016 |
|
rs767649
|
MIR155HG;MIR155
|
Liver carcinoma
|
|
0.010 |
GeneticVariation |
BEFREE |
Our findings suggested that miR-155 and its functional variant rs767649 might contribute to the increased risk and poor prognosis of HCC, highlighting the importance of miR-155 in the prevention and prognosis of HCC.
|
27531892 |
2016 |
|
rs767649
|
MIR155HG;MIR155
|
Cervix carcinoma
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, rs767649 might be a causal variant for CC susceptibility.
|
27717891 |
2016 |
|
rs767649
|
MIR155HG;MIR155
|
Adenocarcinoma of lung (disorder)
|
|
0.010 |
GeneticVariation |
BEFREE |
Furthermore, using functional assays and The Cancer Genome Atlas (TCGA) Lung Adenocarcinoma (LUAD) dataset, we found that rs767649 variant allele could increase the transcriptional activity of miR-155, which in turn facilitated tumor growth and metastasis by inhibiting HBP1, TJP1, SMAD5 and PRKAR1A expression.
|
26543233 |
2015 |
|
rs767649
|
MIR155HG;MIR155
|
Neoplasm Metastasis
|
|
0.010 |
GeneticVariation |
BEFREE |
Furthermore, using functional assays and The Cancer Genome Atlas (TCGA) Lung Adenocarcinoma (LUAD) dataset, we found that rs767649 variant allele could increase the transcriptional activity of miR-155, which in turn facilitated tumor growth and metastasis by inhibiting HBP1, TJP1, SMAD5 and PRKAR1A expression.
|
26543233 |
2015 |
|
rs767649
|
MIR155HG;MIR155
|
Non-Small Cell Lung Carcinoma
|
|
0.010 |
GeneticVariation |
BEFREE |
Our findings suggested that rs767649 A > T might contribute to the increased risk and poor prognosis of NSCLC, highlighting the importance of rs767649 in the prevention and therapy of NSCLC.
|
26543233 |
2015 |