MIR19A, microRNA 19a, 406979

N. diseases: 151; N. variants: 3
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4284505
rs4284505
Entrez Id: 406952;406953;406979;406980;406982;407975
Gene Symbol: MIR17;MIR18A;MIR19A;MIR19B1;MIR20A;MIR17HG
MIR17;MIR18A;MIR19A;MIR19B1;MIR20A;MIR17HG
CUI: C0026764
Disease:
Multiple Myeloma 		0.010 GeneticVariation BEFREE Haplotype AC (rs4284505</span>-rs1428) and CA (rs7336610-rs4284505) evidently reduce MM risk, whereas haplotype GC (rs4284505-rs1428) significantly elevated MM risk (all P < .05). 31029648 2019
dbSNP: rs770419845
rs770419845
Entrez Id: 406952;406953;406979;406980;406982;407048;407975
Gene Symbol: MIR17;MIR18A;MIR19A;MIR19B1;MIR20A;MIR92A1;MIR17HG
MIR17;MIR18A;MIR19A;MIR19B1;MIR20A;MIR92A1;MIR17HG
CUI: C0678222
Disease:
Breast Carcinoma 		0.010 GeneticVariation BEFREE The deletion was screened in 458 high-risk <i>BRCA1/2</i>-negative Chilean families and 480 controls. rs770419845 was not detected in any control but identified in a single family with two cases of BC and other cancers. 29361751 2018
dbSNP: rs770419845
rs770419845
Entrez Id: 406952;406953;406979;406980;406982;407048;407975
Gene Symbol: MIR17;MIR18A;MIR19A;MIR19B1;MIR20A;MIR92A1;MIR17HG
MIR17;MIR18A;MIR19A;MIR19B1;MIR20A;MIR92A1;MIR17HG
CUI: C1611743
Disease:
Familial (FPAH) 		0.010 GeneticVariation BEFREE Here, we report the identification of rs770419845, a rare 6 bp deletion located within the polycistronic miR-17-92 cluster, in two first-degree relatives from a Chilean family with familial BC and negative for point mutations in <i>BRCA 1/2</i> genes. 29361751 2018
dbSNP: rs770419845
rs770419845
Entrez Id: 406952;406953;406979;406980;406982;407048;407975
Gene Symbol: MIR17;MIR18A;MIR19A;MIR19B1;MIR20A;MIR92A1;MIR17HG
MIR17;MIR18A;MIR19A;MIR19B1;MIR20A;MIR92A1;MIR17HG
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.010 GeneticVariation BEFREE The deletion was screened in 458 high-risk <i>BRCA1/2</i>-negative Chilean families and 480 controls. rs770419845 was not detected in any control but identified in a single family with two cases of BC and other cancers. 29361751 2018
dbSNP: rs9589207
rs9589207
Entrez Id: 406979;406980;406982;407048;407975
Gene Symbol: MIR19A;MIR19B1;MIR20A;MIR92A1;MIR17HG
MIR19A;MIR19B1;MIR20A;MIR92A1;MIR17HG
CUI: C0024623
Disease:
Malignant neoplasm of stomach 		0.010 GeneticVariation BEFREE In conclusion, rs9589207 in miR-92a was highly associated with a decreased risk of GC in Chinese Han population and might serve as a novel biomarker for the disease. 26499948 2016
dbSNP: rs9589207
rs9589207
Entrez Id: 406979;406980;406982;407048;407975
Gene Symbol: MIR19A;MIR19B1;MIR20A;MIR92A1;MIR17HG
MIR19A;MIR19B1;MIR20A;MIR92A1;MIR17HG
CUI: C0027651
Disease:
Neoplasms 		0.010 GeneticVariation BEFREE We found that rs9589207 in miR-92a was involved in the occurrence of GC by acting as a tumor protective factor and was highly associated with tumor size in GC patients instead of tumor number or metastasis in 554 GC patients and 531 cancer-free controls. 26499948 2016
dbSNP: rs9589207
rs9589207
Entrez Id: 406979;406980;406982;407048;407975
Gene Symbol: MIR19A;MIR19B1;MIR20A;MIR92A1;MIR17HG
MIR19A;MIR19B1;MIR20A;MIR92A1;MIR17HG
CUI: C0027627
Disease:
Neoplasm Metastasis 		0.010 GeneticVariation BEFREE We found that rs9589207 in miR-92a was involved in the occurrence of GC by acting as a tumor protective factor and was highly associated with tumor size in GC patients instead of tumor number or metastasis in 554 GC patients and 531 cancer-free controls. 26499948 2016
dbSNP: rs9589207
rs9589207
Entrez Id: 406979;406980;406982;407048;407975
Gene Symbol: MIR19A;MIR19B1;MIR20A;MIR92A1;MIR17HG
MIR19A;MIR19B1;MIR20A;MIR92A1;MIR17HG
CUI: C0699791
Disease:
Stomach Carcinoma 		0.010 GeneticVariation BEFREE In conclusion, rs9589207 in miR-92a was highly associated with a decreased risk of GC in Chinese Han population and might serve as a novel biomarker for the disease. 26499948 2016