MBL2, mannose binding lectin 2, 4153

N. diseases: 563; N. variants: 21
Disease: Cystic Fibrosis ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs5030737
rs5030737
Entrez Id: 4153
Gene Symbol: MBL2
MBL2
CUI: C0010674
Disease:
Cystic Fibrosis 		A 0.700 SusceptibilityMutation CLINVAR
dbSNP: rs11003125
rs11003125
Entrez Id: 4153
Gene Symbol: MBL2
MBL2
CUI: C0010674
Disease:
Cystic Fibrosis 		0.010 GeneticVariation BEFREE When we used the dominant model, the MBL2 allele rs11003125 (MBL2-550; p = 0.022, Odds Ratio (OR) 2.87, 95% CI 1.14-7.27) was significantly associated with CF patients as risk factor, and the ADRB2 allele rs1042713 (p.Arg16Gly; p = 0.005, Odds Ratio (OR) 0.37, 95% CI 0.19-0.75) was significantly associated with CF patients as protect factor. 29703608 2018