MDM2, MDM2 proto-oncogene, 4193

N. diseases: 702; N. variants: 30
Disease: Adenocarcinoma of lung (disorder) ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs746284240
rs746284240
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
CUI: C0152013
Disease:
Adenocarcinoma of lung (disorder) 		0.010 GeneticVariation BEFREE However, these profiles did not segregate by histology (lung adenocarcinoma-appendiceal cancer (KRAS G12D and GNAS R201C), and lung adenocarcinoma-liposarcoma (CDK4 and MDM2 amplification pairs)). 26418953 2015
dbSNP: rs1353702185
rs1353702185
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
CUI: C0152013
Disease:
Adenocarcinoma of lung (disorder) 		0.010 GeneticVariation BEFREE P53 Arg72Pro and MDM2 SNP309 polymorphisms, either alone or in combination, are associated with an increased lung adenocarcinoma risk in Chinese female non-smokers. 24175836 2013
dbSNP: rs2279744
rs2279744
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
CUI: C0152013
Disease:
Adenocarcinoma of lung (disorder) 		0.010 GeneticVariation BEFREE We investigated the distribution of the p53 Arg72Pro (rs1042522) and MDM2 SNP309 (rs2279744) genotypes in patients and healthy control subjects to assess whether these single nucleotide polymorphisms (SNPs) are associated with an increased risk of lung adenocarcinomas in Chinese female non- smokers. 24175836 2013