MECP2, methyl-CpG binding protein 2, 4204

N. diseases: 664; N. variants: 387
Disease: Lupus Erythematosus, Systemic ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1734787
rs1734787
Entrez Id: 4204
Gene Symbol: MECP2
MECP2
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		C 0.710 GeneticVariation GWASCAT Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus. 26502338 2015
dbSNP: rs1734787
rs1734787
Entrez Id: 4204
Gene Symbol: MECP2
MECP2
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.710 GeneticVariation BEFREE Our results showed a significant association between rs1734787 and rs1734791 SNPs and the risk of SLE in the Iranian population (p = 0.028, p = 0.028), but did not show any significant association with rs1734792 and rs17435 SNPs (p = 075, p = 0.75). 26156810 2015
dbSNP: rs2075596
rs2075596
Entrez Id: 4204
Gene Symbol: MECP2
MECP2
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.020 GeneticVariation BEFREE The rs2239464 and rs2075596 polymorphisms of MECP2 might play a significant role in the development of SLE in the Northern Han of China. 26782401 2015
dbSNP: rs2239464
rs2239464
Entrez Id: 4204
Gene Symbol: MECP2
MECP2
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.020 GeneticVariation BEFREE The rs2239464 and rs2075596 polymorphisms of MECP2 might play a significant role in the development of SLE in the Northern Han of China. 26782401 2015
dbSNP: rs2075596
rs2075596
Entrez Id: 4204
Gene Symbol: MECP2
MECP2
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.020 GeneticVariation BEFREE Mutations of SNPs (rs2075596, rs2239464) of MeCP2 showed increased risk of developing SLE. 23857988 2013
dbSNP: rs2239464
rs2239464
Entrez Id: 4204
Gene Symbol: MECP2
MECP2
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.020 GeneticVariation BEFREE Mutations of SNPs (rs2075596, rs2239464) of MeCP2 showed increased risk of developing SLE. 23857988 2013
dbSNP: rs1734791
rs1734791
Entrez Id: 4204
Gene Symbol: MECP2
MECP2
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.010 GeneticVariation BEFREE Our results showed a significant association between rs1734787 and rs1734791 SNPs and the risk of SLE in the Iranian population (p = 0.028, p = 0.028), but did not show any significant association with rs1734792 and rs17435 SNPs (p = 075, p = 0.75). 26156810 2015
dbSNP: rs1734792
rs1734792
Entrez Id: 4204
Gene Symbol: MECP2
MECP2
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.010 GeneticVariation BEFREE Our results showed a significant association between rs1734787 and rs1734791 SNPs and the risk of SLE in the Iranian population (p = 0.028, p = 0.028), but did not show any significant association with rs1734792 and rs17435 SNPs (p = 075, p = 0.75). 26156810 2015
dbSNP: rs17435
rs17435
Entrez Id: 4204
Gene Symbol: MECP2
MECP2
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.010 GeneticVariation BEFREE Our results showed a significant association between rs1734787 and rs1734791 SNPs and the risk of SLE in the Iranian population (p = 0.028, p = 0.028), but did not show any significant association with rs1734792 and rs17435 SNPs (p = 075, p = 0.75). 26156810 2015