MGMT, O-6-methylguanine-DNA methyltransferase, 4255

N. diseases: 444; N. variants: 24
Disease: Malignant neoplasm of mouth ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12917
rs12917
Entrez Id: 4255;105378560
Gene Symbol: MGMT;LOC105378560
MGMT;LOC105378560
CUI: C0153381
Disease:
Malignant neoplasm of mouth 		0.010 GeneticVariation BEFREE The present study did not find statistically significant association between six common MGMT polymorphisms and oral cancer risk, however, both MGMT L53L and L84F polymorphisms in old patients with CT genotype have higher overall survival rates than patients with CC genotype. 20412404 2010