MMP3, matrix metallopeptidase 3, 4314

N. diseases: 473; N. variants: 24
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs566125
rs566125
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C1704436
Disease:
Peripheral Arterial Diseases 		T 0.700 GeneticVariation GWASCAT Genome-wide association study of peripheral artery disease in the Million Veteran Program. 31285632 2019
dbSNP: rs575027
rs575027
Entrez Id: 4314;100288077
Gene Symbol: MMP3;WTAPP1
MMP3;WTAPP1
CUI: C2985280
Disease:
Blood Protein Measurement 		G 0.700 GeneticVariation GWASCAT Co-regulatory networks of human serum proteins link genetics to disease. 30072576 2018
dbSNP: rs1892875
rs1892875
Entrez Id: 4314;100288077
Gene Symbol: MMP3;WTAPP1
MMP3;WTAPP1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		G 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs639752
rs639752
Entrez Id: 4314;100288077
Gene Symbol: MMP3;WTAPP1
MMP3;WTAPP1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		A 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs476762
rs476762
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C3548479
Disease:
response to bronchodilator 		A 0.700 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245 2015
dbSNP: rs476762
rs476762
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C0024117
Disease:
Chronic Obstructive Airway Disease 		A 0.700 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245 2015
dbSNP: rs494963
rs494963
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C0024117
Disease:
Chronic Obstructive Airway Disease 		A 0.700 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245 2015
dbSNP: rs494963
rs494963
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C3548479
Disease:
response to bronchodilator 		A 0.700 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245 2015
dbSNP: rs563096
rs563096
Entrez Id: 4314;100288077
Gene Symbol: MMP3;WTAPP1
MMP3;WTAPP1
CUI: C0024117
Disease:
Chronic Obstructive Airway Disease 		A 0.700 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245 2015
dbSNP: rs563096
rs563096
Entrez Id: 4314;100288077
Gene Symbol: MMP3;WTAPP1
MMP3;WTAPP1
CUI: C3548479
Disease:
response to bronchodilator 		A 0.700 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245 2015
dbSNP: rs566125
rs566125
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C3548479
Disease:
response to bronchodilator 		T 0.700 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245 2015
dbSNP: rs566125
rs566125
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C0024117
Disease:
Chronic Obstructive Airway Disease 		T 0.700 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245 2015
dbSNP: rs569444
rs569444
Entrez Id: 4314;100288077
Gene Symbol: MMP3;WTAPP1
MMP3;WTAPP1
CUI: C3548479
Disease:
response to bronchodilator 		A 0.700 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245 2015
dbSNP: rs569444
rs569444
Entrez Id: 4314;100288077
Gene Symbol: MMP3;WTAPP1
MMP3;WTAPP1
CUI: C0024117
Disease:
Chronic Obstructive Airway Disease 		A 0.700 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245 2015
dbSNP: rs646910
rs646910
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C0024117
Disease:
Chronic Obstructive Airway Disease 		A 0.700 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245 2015
dbSNP: rs646910
rs646910
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C3548479
Disease:
response to bronchodilator 		A 0.700 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245 2015
dbSNP: rs655403
rs655403
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C0024117
Disease:
Chronic Obstructive Airway Disease 		T 0.700 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245 2015
dbSNP: rs655403
rs655403
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C3548479
Disease:
response to bronchodilator 		T 0.700 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245 2015
dbSNP: rs680753
rs680753
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C0024117
Disease:
Chronic Obstructive Airway Disease 		C 0.700 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245 2015
dbSNP: rs680753
rs680753
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C3548479
Disease:
response to bronchodilator 		C 0.700 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245 2015
dbSNP: rs3025063
rs3025063
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C0392885
Disease:
High density lipoprotein measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs3025063
rs3025063
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C0428472
Disease:
Serum HDL cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs679620
rs679620
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C3840085
Disease:
Disorder of Achilles tendon 		0.030 GeneticVariation BEFREE Two SNPs, rs679620 (OR=0.82, P=0.0006, MMP3) and rs4789932 (OR=1.2, P=0.0002, TIMP2) were identified to be significantly associated with chronic AT risk. 31208828 2019
dbSNP: rs3025058
rs3025058
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C0948008
Disease:
Ischemic stroke 		0.030 GeneticVariation BEFREE Our findings indicate that the rs679620 A allele carriers have increased risk of ischemic stroke in Asians, but there is no association between rs3025058 and ischemic stroke risk. 29440903 2018
dbSNP: rs679620
rs679620
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C3840085
Disease:
Disorder of Achilles tendon 		0.030 GeneticVariation BEFREE Based on high linkage with the previously associated MMP3 variant rs679620, rs3025058 was inferred and found to be associated with increased risk for Achilles tendinopathy within the South African group (P = 0.012; OR: 2.88; 95% CI: 1.4 to 6.1). 27211292 2017