MTAP, methylthioadenosine phosphorylase, 4507

N. diseases: 167; N. variants: 19
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs7023329
rs7023329
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
CUI: C0025202
Disease:
melanoma 		0.810 GeneticVariation GWASCAT Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma. 28212542 2017
dbSNP: rs7023329
rs7023329
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
CUI: C0025202
Disease:
melanoma 		0.810 GeneticVariation BEFREE One SNP in MTAP (methylthioadenosine phosphorylase) (rs7023329) that was previously associated with melanoma and nevi in multiple genome-wide association studies was associated with CRC, CA and OS by ASSET (P=0.007). 23361049 2013
dbSNP: rs7023329
rs7023329
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
CUI: C0025202
Disease:
melanoma 		0.810 GeneticVariation GWASDB A unique genome-wide association analysis in extended Utah high-risk pedigrees identifies a novel melanoma risk variant on chromosome arm 10q. 21706340 2012
dbSNP: rs7023329
rs7023329
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
CUI: C0025202
Disease:
melanoma 		0.810 GeneticVariation GWASCAT Genome-wide association study identifies three new melanoma susceptibility loci. 21983787 2011
dbSNP: rs7023329
rs7023329
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
CUI: C0025202
Disease:
melanoma 		0.810 GeneticVariation GWASDB Genome-wide association study identifies three new melanoma susceptibility loci. 21983787 2011
dbSNP: rs7023329
rs7023329
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
CUI: C0025202
Disease:
melanoma 		A 0.810 GeneticVariation GWASCAT Genome-wide association study identifies three loci associated with melanoma risk. 19578364 2009
dbSNP: rs7023329
rs7023329
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
CUI: C0025202
Disease:
melanoma 		A 0.810 GeneticVariation GWASDB Genome-wide association study identifies three loci associated with melanoma risk. 19578364 2009
dbSNP: rs10757257
rs10757257
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
CUI: C0025202
Disease:
melanoma 		0.710 GeneticVariation GWASDB A unique genome-wide association analysis in extended Utah high-risk pedigrees identifies a novel melanoma risk variant on chromosome arm 10q. 21706340 2012
dbSNP: rs10757257
rs10757257
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
CUI: C0025202
Disease:
melanoma 		0.710 GeneticVariation BEFREE In addition, variants in these two loci showed association with melanoma risk in 3,131 melanoma cases from two independent studies, including rs10757257 at 9p21, combined P = 3.4 x 10(-8), OR = 1.23 (95% CI = 1.15-1.30) and rs132985 at 22q13.1, combined P = 2.6 x 10(-7), OR = 1.23 (95% CI = 1.15-1.30). 19578365 2009
dbSNP: rs67134687
rs67134687
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
CUI: C0869220
Disease:
Adverse effects, not elsewhere classified 		G 0.700 GeneticVariation GWASCAT Genetic variation in the Estonian population: pharmacogenomics study of adverse drug effects using electronic health records. 30420678 2019
dbSNP: rs11532907
rs11532907
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
CUI: C0151779
Disease:
Cutaneous Melanoma 		0.700 GeneticVariation GWASCAT Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways. 30429480 2018
dbSNP: rs11532907
rs11532907
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
CUI: C0153535
Disease:
Malignant melanoma of skin of upper limb 		0.700 GeneticVariation GWASCAT Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways. 30429480 2018
dbSNP: rs11532907
rs11532907
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
CUI: C0153536
Disease:
Malignant melanoma of skin of lower limb 		0.700 GeneticVariation GWASCAT Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways. 30429480 2018
dbSNP: rs869329
rs869329
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
CUI: C0151779
Disease:
Cutaneous Melanoma 		0.700 GeneticVariation GWASCAT Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways. 30429480 2018
dbSNP: rs869329
rs869329
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
CUI: C0153535
Disease:
Malignant melanoma of skin of upper limb 		0.700 GeneticVariation GWASCAT Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways. 30429480 2018
dbSNP: rs869329
rs869329
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
CUI: C0153536
Disease:
Malignant melanoma of skin of lower limb 		0.700 GeneticVariation GWASCAT Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways. 30429480 2018
dbSNP: rs201131773
rs201131773
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
CUI: C0025202
Disease:
melanoma 		0.700 GeneticVariation GWASCAT Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma. 28212542 2017
dbSNP: rs4364717
rs4364717
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
CUI: C0428883
Disease:
Diastolic blood pressure 		A 0.700 GeneticVariation GWASCAT Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. 28135244 2017
dbSNP: rs885518
rs885518
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
CUI: C0152013
Disease:
Adenocarcinoma of lung (disorder) 		G 0.700 GeneticVariation GWASCAT Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. 28604730 2017
dbSNP: rs185224597
rs185224597
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
CUI: C0016529
Disease:
Forced expiratory volume function 		C 0.700 GeneticVariation GWASCAT Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank. 26423011 2015
dbSNP: rs7851133
rs7851133
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
CUI: C0014859
Disease:
Esophageal Neoplasms 		0.700 GeneticVariation GWASDB Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. 22960999 2012
dbSNP: rs7023329
rs7023329
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
CUI: C2931822
Disease:
Nasopharyngeal carcinoma 		0.700 GeneticVariation GWASDB A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci. 20512145 2010
dbSNP: rs10811625
rs10811625
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
CUI: C0027960
Disease:
Nevus 		0.700 GeneticVariation GWASDB Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi. 19578365 2009
dbSNP: rs10965144
rs10965144
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
CUI: C0027960
Disease:
Nevus 		0.700 GeneticVariation GWASDB Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi. 19578365 2009
dbSNP: rs3900787
rs3900787
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
CUI: C0027960
Disease:
Nevus 		0.700 GeneticVariation GWASDB Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi. 19578365 2009