rs36053993
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Stomach Neoplasms
T
0.700
CausalMutation
CLINVAR
MUTYH-associated polyposis (MAP): evidence for the origin of the common European mutations p.Tyr179Cys and p.Gly396Asp by founder events.
23361220
2014
rs36053993
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Stomach Neoplasms
T
0.700
CausalMutation
CLINVAR
Germline variation in cancer-susceptibility genes in a healthy, ancestrally diverse cohort: implications for individual genome sequencing.
24728327
2014
rs36053993
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Stomach Neoplasms
T
0.700
CausalMutation
CLINVAR
Germline Mutations in the Polyposis-Associated Genes BMPR1A, SMAD4, PTEN, MUTYH and GREM1 Are Not Common in Individuals with Serrated Polyposis Syndrome.
23805267
2013
rs36053993
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Stomach Neoplasms
T
0.700
CausalMutation
CLINVAR
Loss of MUTYH function in human cells leads to accumulation of oxidative damage and genetic instability.
23108399
2013
rs36053993
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Stomach Neoplasms
T
0.700
CausalMutation
CLINVAR
Personalized genomic disease risk of volunteers.
24082139
2013
rs36053993
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Stomach Neoplasms
T
0.700
CausalMutation
CLINVAR
Colorectal cancer in a monoallelic MYH mutation carrier.
23625202
2013
rs36053993
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Stomach Neoplasms
T
0.700
CausalMutation
CLINVAR
Secondary variants in individuals undergoing exome sequencing: screening of 572 individuals identifies high-penetrance mutations in cancer-susceptibility genes.
22703879
2012
rs36053993
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Stomach Neoplasms
T
0.700
CausalMutation
CLINVAR
MUTYH gene expression and alternative splicing in controls and polyposis patients.
22473953
2012
rs36053993
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Stomach Neoplasms
T
0.700
CausalMutation
CLINVAR
MutYH mutation carriers have increased breast cancer risk.
21952991
2012
rs36053993
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Stomach Neoplasms
T
0.700
CausalMutation
CLINVAR
High prevalence of the c.1227_1228dup (p.Glu410GlyfsX43) mutation in Tunisian families affected with MUTYH-associated-polyposis.
22744763
2012
rs36053993
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Stomach Neoplasms
T
0.700
CausalMutation
CLINVAR
Cancer-associated variants and a common polymorphism of MUTYH exhibit reduced repair of oxidative DNA damage using a GFP-based assay in mammalian cells.
22926731
2012
rs36053993
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Stomach Neoplasms
T
0.700
CausalMutation
CLINVAR
MUTYH-associated colon disease: adenomatous polyposis is only one of the possible phenotypes. A family report and literature review.
22158503
2012
rs36053993
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Stomach Neoplasms
T
0.700
CausalMutation
CLINVAR
Functional analysis of MUTYH mutated proteins associated with familial adenomatous polyposis.
20418187
2010
rs36053993
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Stomach Neoplasms
T
0.700
CausalMutation
CLINVAR
Adenine DNA glycosylase activity of 14 human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancer.
20848659
2010
rs36053993
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Stomach Neoplasms
T
0.700
CausalMutation
CLINVAR
Rectum-sparing surgery may be appropriate for biallelic MutYH-associated polyposis.
21178863
2010
rs36053993
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Stomach Neoplasms
T
0.700
CausalMutation
CLINVAR
MUTYH mutations associated with familial adenomatous polyposis: functional characterization by a mammalian cell-based assay.
19953527
2010
rs36053993
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Stomach Neoplasms
T
0.700
CausalMutation
CLINVAR
Biallelic MYH germline mutations as cause of Muir-Torre syndrome.
19998059
2010
rs36053993
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Stomach Neoplasms
T
0.700
CausalMutation
CLINVAR
A large-scale meta-analysis to refine colorectal cancer risk estimates associated with MUTYH variants.
21063410
2010
rs36053993
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Stomach Neoplasms
T
0.700
CausalMutation
CLINVAR
Adenine removal activity and bacterial complementation with the human MutY homologue (MUTYH) and Y165C, G382D, P391L and Q324R variants associated with colorectal cancer.
19836313
2009
rs36053993
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Stomach Neoplasms
T
0.700
CausalMutation
CLINVAR
Expanded extracolonic tumor spectrum in MUTYH-associated polyposis.
19732775
2009
rs36053993
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Stomach Neoplasms
T
0.700
CausalMutation
CLINVAR
Analysis of MUTYH genotypes and colorectal phenotypes in patients With MUTYH-associated polyposis.
19032956
2009
rs36053993
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Stomach Neoplasms
T
0.700
CausalMutation
CLINVAR
Characterization of mutant MUTYH proteins associated with familial colorectal cancer.
18534194
2008
rs36053993
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Stomach Neoplasms
T
0.700
CausalMutation
CLINVAR
Inherited variants of MYH associated with somatic G:C-->T:A mutations in colorectal tumors.
11818965
2002
rs121908382
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Stomach Neoplasms
A
0.700
CausalMutation
CLINVAR
rs121908383
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
Stomach Neoplasms
C
0.700
CausalMutation
CLINVAR