ATF4, activating transcription factor 4, 468

N. diseases: 178; N. variants: 4
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1048310
rs1048310
Entrez Id: 468;54471
Gene Symbol: ATF4;MIEF1
ATF4;MIEF1
CUI: C1261502
Disease:
Finding of Mean Corpuscular Hemoglobin 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs148038848
rs148038848
Entrez Id: 468
Gene Symbol: ATF4
ATF4
CUI: C0030567
Disease:
Parkinson Disease 		0.010 GeneticVariation BEFREE Human myeloperoxidase (hMPO) is expressed in neurons in the substantia nigra in Parkinson's disease and in the hMPO-α-synuclein-A53T mouse model, correlating with increased nitration and aggregation of α-synuclein and exacerbation of motor impairment. 31175983 2019
dbSNP: rs17001266
rs17001266
Entrez Id: 468
Gene Symbol: ATF4
ATF4
CUI: C0036341
Disease:
Schizophrenia 		0.010 GeneticVariation BEFREE Two haplotypes CC and -A constructed of rs17001266-rs4894 also revealed significant associations with schizophrenia in male group (global P = 0.0097). 18163433 2008
dbSNP: rs4894
rs4894
Entrez Id: 468
Gene Symbol: ATF4
ATF4
CUI: C0036341
Disease:
Schizophrenia 		0.010 GeneticVariation BEFREE Two haplotypes CC and -A constructed of rs17001266-rs4894 also revealed significant associations with schizophrenia in male group (global P = 0.0097). 18163433 2008