NELL1, neural EGFL like 1, 4745

N. diseases: 122; N. variants: 23
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10741858
rs10741858
Entrez Id: 4745
Gene Symbol: NELL1
NELL1
CUI: C0523465
Disease:
Serum albumin measurement 		0.700 GeneticVariation GWASDB A genome-wide assessment of variability in human serum metabolism. 23281178 2013
dbSNP: rs7950875
rs7950875
Entrez Id: 4745
Gene Symbol: NELL1
NELL1
CUI: C0523465
Disease:
Serum albumin measurement 		0.700 GeneticVariation GWASDB A genome-wide assessment of variability in human serum metabolism. 23281178 2013
dbSNP: rs148586747
rs148586747
Entrez Id: 4745
Gene Symbol: NELL1
NELL1
CUI: C0037369
Disease:
Smoking 		A 0.700 GeneticVariation GWASCAT Genome-wide association study in Finnish twins highlights the connection between nicotine addiction and neurotrophin signaling pathway. 29532581 2019
dbSNP: rs1670661
rs1670661
Entrez Id: 4745
Gene Symbol: NELL1
NELL1
CUI: C0007137
Disease:
Squamous cell carcinoma 		0.010 GeneticVariation BEFREE Multifactor dimensionality reduction analysis showed that the interactions among HPV and NELL1 variant rs1670661 with age and gender augmented the risk of both non-tobacco- and tobacco-related oral squamous cell carcinoma, respectively. 30091681 2018
dbSNP: rs12279250
rs12279250
Entrez Id: 4745
Gene Symbol: NELL1
NELL1
CUI: C0202236
Disease:
Triglycerides measurement 		C 0.700 GeneticVariation GWASCAT Two single-nucleotide polymorphisms (rs12279250 and rs4319515 (r(2)=0.73)), located at 11p15.1 in the NELL1 gene, achieved genome-wide significance for association with change in fasting plasma triglycerides in African Americans, whereby each variant allele was associated with a 28 mg dl(-1) increase in the change in triglycerides. 23400010 2014