NRAS, NRAS proto-oncogene, GTPase, 4893

N. diseases: 611; N. variants: 17
Disease: Papilloma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1057519695
rs1057519695
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0030354
Disease:
Papilloma 		0.010 GeneticVariation BEFREE DMBA/TPA treatment of Hras(G12V) knock-in mice induced an even greater incidence of papillomas, which either harbored Hras(G12V) amplification or developed an Hras(Q61L) mutation in the second allele. 24240680 2014
dbSNP: rs11554290
rs11554290
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0030354
Disease:
Papilloma 		0.010 GeneticVariation BEFREE DMBA/TPA treatment of Hras(G12V) knock-in mice induced an even greater incidence of papillomas, which either harbored Hras(G12V) amplification or developed an Hras(Q61L) mutation in the second allele. 24240680 2014
dbSNP: rs121913237
rs121913237
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0030354
Disease:
Papilloma 		0.010 GeneticVariation BEFREE Hras(G12V) allele copy number was increased in all papillomas induced by TPA. 24240680 2014
dbSNP: rs121913255
rs121913255
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0030354
Disease:
Papilloma 		0.010 GeneticVariation BEFREE The 10 papillary carcinomas showed an overall lower frequency of mutations, including 1 with an AKT1 mutation (in a tumor arising from a papilloma), 1 with an NRAS gene mutation (Q61H), and 2 with PIK3CA mutations (1 overlapping with the NRAS Q61H). 19898424 2010