Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1354034
rs1354034
Entrez Id: 50650
Gene Symbol: ARHGEF3
ARHGEF3
CUI: C0032181
Disease:
Platelet Count measurement 		0.800 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584 2019
dbSNP: rs1354034
rs1354034
Entrez Id: 50650
Gene Symbol: ARHGEF3
ARHGEF3
CUI: C0200665
Disease:
Platelet mean volume determination (procedure) 		T 0.800 GeneticVariation GWASCAT The two strongest associations were SNP rs1354034 with MPV (p = 2.4x10-13) and rs855791 with MCV (p = 5.2x10-12). 31194788 2019
dbSNP: rs1354034
rs1354034
Entrez Id: 50650
Gene Symbol: ARHGEF3
ARHGEF3
CUI: C0032181
Disease:
Platelet Count measurement 		0.800 GeneticVariation GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010 2018
dbSNP: rs1354034
rs1354034
Entrez Id: 50650
Gene Symbol: ARHGEF3
ARHGEF3
CUI: C0032181
Disease:
Platelet Count measurement 		0.800 GeneticVariation GWASCAT 2SNP heritability and effects of genetic variants for neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio. 29066854 2017
dbSNP: rs1354034
rs1354034
Entrez Id: 50650
Gene Symbol: ARHGEF3
ARHGEF3
CUI: C0032181
Disease:
Platelet Count measurement 		C 0.800 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs1354034
rs1354034
Entrez Id: 50650
Gene Symbol: ARHGEF3
ARHGEF3
CUI: C0200665
Disease:
Platelet mean volume determination (procedure) 		C 0.800 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs1354034
rs1354034
Entrez Id: 50650
Gene Symbol: ARHGEF3
ARHGEF3
CUI: C0032181
Disease:
Platelet Count measurement 		T 0.800 GeneticVariation GWASCAT Genome-wide Association Study of Platelet Count Identifies Ancestry-Specific Loci in Hispanic/Latino Americans. 26805783 2016
dbSNP: rs1354034
rs1354034
Entrez Id: 50650
Gene Symbol: ARHGEF3
ARHGEF3
CUI: C0032181
Disease:
Platelet Count measurement 		T 0.800 GeneticVariation GWASDB A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects. 24026423 2014
dbSNP: rs1354034
rs1354034
Entrez Id: 50650
Gene Symbol: ARHGEF3
ARHGEF3
CUI: C0200665
Disease:
Platelet mean volume determination (procedure) 		C 0.800 GeneticVariation GWASDB A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects. 24026423 2014
dbSNP: rs1354034
rs1354034
Entrez Id: 50650
Gene Symbol: ARHGEF3
ARHGEF3
CUI: C0200665
Disease:
Platelet mean volume determination (procedure) 		C 0.800 GeneticVariation GWASCAT A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects. 24026423 2014
dbSNP: rs1354034
rs1354034
Entrez Id: 50650
Gene Symbol: ARHGEF3
ARHGEF3
CUI: C0032181
Disease:
Platelet Count measurement 		T 0.800 GeneticVariation GWASCAT A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects. 24026423 2014
dbSNP: rs1354034
rs1354034
Entrez Id: 50650
Gene Symbol: ARHGEF3
ARHGEF3
CUI: C0032181
Disease:
Platelet Count measurement 		T 0.800 GeneticVariation GWASDB GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children. 23263863 2013
dbSNP: rs1354034
rs1354034
Entrez Id: 50650
Gene Symbol: ARHGEF3
ARHGEF3
CUI: C0032181
Disease:
Platelet Count measurement 		C 0.800 GeneticVariation GWASDB GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children. 23263863 2013
dbSNP: rs1354034
rs1354034
Entrez Id: 50650
Gene Symbol: ARHGEF3
ARHGEF3
CUI: C0032181
Disease:
Platelet Count measurement 		C 0.800 GeneticVariation GWASCAT GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children. 23263863 2013
dbSNP: rs1354034
rs1354034
Entrez Id: 50650
Gene Symbol: ARHGEF3
ARHGEF3
CUI: C0032181
Disease:
Platelet Count measurement 		T 0.800 GeneticVariation GWASCAT GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children. 23263863 2013
dbSNP: rs12485738
rs12485738
Entrez Id: 50650
Gene Symbol: ARHGEF3
ARHGEF3
CUI: C0200665
Disease:
Platelet mean volume determination (procedure) 		0.800 GeneticVariation GWASDB A meta-analysis and genome-wide association study of platelet count and mean platelet volume in african americans. 22423221 2012
dbSNP: rs1354034
rs1354034
Entrez Id: 50650
Gene Symbol: ARHGEF3
ARHGEF3
CUI: C0032181
Disease:
Platelet Count measurement 		C 0.800 GeneticVariation GWASCAT New gene functions in megakaryopoiesis and platelet formation. 22139419 2011
dbSNP: rs1354034
rs1354034
Entrez Id: 50650
Gene Symbol: ARHGEF3
ARHGEF3
CUI: C0032181
Disease:
Platelet Count measurement 		C 0.800 GeneticVariation GWASDB New gene functions in megakaryopoiesis and platelet formation. 22139419 2011
dbSNP: rs1354034
rs1354034
Entrez Id: 50650
Gene Symbol: ARHGEF3
ARHGEF3
CUI: C0200665
Disease:
Platelet mean volume determination (procedure) 		T 0.800 GeneticVariation GWASCAT New gene functions in megakaryopoiesis and platelet formation. 22139419 2011
dbSNP: rs1354034
rs1354034
Entrez Id: 50650
Gene Symbol: ARHGEF3
ARHGEF3
CUI: C0200665
Disease:
Platelet mean volume determination (procedure) 		C 0.800 GeneticVariation GWASDB New gene functions in megakaryopoiesis and platelet formation. 22139419 2011
dbSNP: rs12485738
rs12485738
Entrez Id: 50650
Gene Symbol: ARHGEF3
ARHGEF3
CUI: C0200665
Disease:
Platelet mean volume determination (procedure) 		A 0.800 GeneticVariation GWASDB A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. 19820697 2009
dbSNP: rs12485738
rs12485738
Entrez Id: 50650
Gene Symbol: ARHGEF3
ARHGEF3
CUI: C0200665
Disease:
Platelet mean volume determination (procedure) 		A 0.800 GeneticVariation GWASCAT We conducted a genome-wide association study (GWAS), the KORA (Kooperative Gesundheitsforschung in der Region Augsburg) F3 500K study, and found MPV to be strongly associated with three common single-nucleotide polymorphisms (SNPs): rs7961894 located within intron 3 of WDR66 on chromosome 12q24.31, rs12485738 upstream of the ARHGEF3 on chromosome 3p13-p21, and rs2138852 located upstream of TAOK1 on chromosome 17q11.2. 19110211 2009
dbSNP: rs12485738
rs12485738
Entrez Id: 50650
Gene Symbol: ARHGEF3
ARHGEF3
CUI: C0200665
Disease:
Platelet mean volume determination (procedure) 		A 0.800 GeneticVariation GWASCAT A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. 19820697 2009
dbSNP: rs12485738
rs12485738
Entrez Id: 50650
Gene Symbol: ARHGEF3
ARHGEF3
CUI: C0200665
Disease:
Platelet mean volume determination (procedure) 		A 0.800 GeneticVariation GWASDB We conducted a genome-wide association study (GWAS), the KORA (Kooperative Gesundheitsforschung in der Region Augsburg) F3 500K study, and found MPV to be strongly associated with three common single-nucleotide polymorphisms (SNPs): rs7961894 located within intron 3 of WDR66 on chromosome 12q24.31, rs12485738 upstream of the ARHGEF3 on chromosome 3p13-p21, and rs2138852 located upstream of TAOK1 on chromosome 17q11.2. 19110211 2009
dbSNP: rs4681794
rs4681794
Entrez Id: 50650
Gene Symbol: ARHGEF3
ARHGEF3
CUI: C0871470
Disease:
Systolic Pressure 		C 0.700 GeneticVariation GWASCAT Trans-ethnic association study of blood pressure determinants in over 750,000 individuals. 30578418 2019