Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs35658696
rs35658696
Entrez Id: 5066
Gene Symbol: PAM
PAM
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		G 0.710 GeneticVariation GWASCAT Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes. 29632382 2018
dbSNP: rs78408340
rs78408340
Entrez Id: 5066
Gene Symbol: PAM
PAM
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		G 0.710 GeneticVariation GWASCAT Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. 30054458 2018
dbSNP: rs35658696
rs35658696
Entrez Id: 5066
Gene Symbol: PAM
PAM
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.710 GeneticVariation BEFREE In addition, two missense variants in PAM, encoding p.Asp563Gly (frequency of 4.98%) and p.Ser539Trp (frequency of 0.65%), confer moderately higher risk of T2D (OR = 1.23, P = 3.9 × 10(-10) and OR = 1.47, P = 1.7 × 10(-5), respectively), and a rare (0.20%) frameshift variant in PDX1, encoding p.Gly218Alafs*12, associates with high risk of T2D (OR = 2.27, P = 7.3 × 10(-7)). 24464100 2014
dbSNP: rs78408340
rs78408340
Entrez Id: 5066
Gene Symbol: PAM
PAM
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.710 GeneticVariation BEFREE In addition, two missense variants in PAM, encoding p.Asp563Gly (frequency of 4.98%) and p.Ser539Trp (frequency of 0.65%), confer moderately higher risk of T2D (OR = 1.23, P = 3.9 × 10(-10) and OR = 1.47, P = 1.7 × 10(-5), respectively), and a rare (0.20%) frameshift variant in PDX1, encoding p.Gly218Alafs*12, associates with high risk of T2D (OR = 2.27, P = 7.3 × 10(-7)). 24464100 2014
dbSNP: rs17154889
rs17154889
Entrez Id: 5066
Gene Symbol: PAM
PAM
CUI: C0205682
Disease:
Waist-Hip Ratio 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs2431320
rs2431320
Entrez Id: 5066
Gene Symbol: PAM
PAM
CUI: C0023508
Disease:
White Blood Cell Count procedure 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs3776864
rs3776864
Entrez Id: 5066
Gene Symbol: PAM
PAM
CUI: C0424574
Disease:
Duration of sleep 		A 0.700 GeneticVariation GWASCAT Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates. 30846698 2019
dbSNP: rs56372231
rs56372231
Entrez Id: 5066
Gene Symbol: PAM
PAM
CUI: C0424574
Disease:
Duration of sleep 		T 0.700 GeneticVariation GWASCAT Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates. 30846698 2019
dbSNP: rs6889592
rs6889592
Entrez Id: 5066
Gene Symbol: PAM
PAM
CUI: C0424574
Disease:
Duration of sleep 		A 0.700 GeneticVariation GWASCAT Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways. 30804565 2019
dbSNP: rs72783884
rs72783884
Entrez Id: 5066
Gene Symbol: PAM
PAM
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs74567345
rs74567345
Entrez Id: 5066
Gene Symbol: PAM
PAM
CUI: C0005890
Disease:
Body Height 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs35658696
rs35658696
Entrez Id: 5066
Gene Symbol: PAM
PAM
CUI: C2985280
Disease:
Blood Protein Measurement 		G 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488 2018
dbSNP: rs35658696
rs35658696
Entrez Id: 5066
Gene Symbol: PAM
PAM
CUI: C0021704
Disease:
Intelligence 		0.700 GeneticVariation GWASCAT Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. 29844566 2018
dbSNP: rs41300805
rs41300805
Entrez Id: 5066
Gene Symbol: PAM
PAM
CUI: C2985280
Disease:
Blood Protein Measurement 		C 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488 2018
dbSNP: rs76177300
rs76177300
Entrez Id: 5066
Gene Symbol: PAM
PAM
CUI: C0021704
Disease:
Intelligence 		0.700 GeneticVariation GWASCAT Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. 29844566 2018
dbSNP: rs7729395
rs7729395
Entrez Id: 5066
Gene Symbol: PAM
PAM
CUI: C0429087
Disease:
Electrocardiogram: P-R interval 		T 0.700 GeneticVariation GWASCAT PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity. 30046033 2018
dbSNP: rs7729395
rs7729395
Entrez Id: 5066
Gene Symbol: PAM
PAM
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		T 0.700 GeneticVariation GWASCAT Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. 30054458 2018
dbSNP: rs78408340
rs78408340
Entrez Id: 5066
Gene Symbol: PAM
PAM
CUI: C2985280
Disease:
Blood Protein Measurement 		G 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488 2018
dbSNP: rs80134320
rs80134320
Entrez Id: 5066
Gene Symbol: PAM
PAM
CUI: C0596887
Disease:
mathematical ability 		T 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs10463554
rs10463554
Entrez Id: 5066
Gene Symbol: PAM
PAM
CUI: C0030567
Disease:
Parkinson Disease 		T 0.700 GeneticVariation GWASCAT A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci. 28892059 2017
dbSNP: rs13175330
rs13175330
Entrez Id: 5066
Gene Symbol: PAM
PAM
CUI: C0428883
Disease:
Diastolic blood pressure 		0.700 GeneticVariation GWASCAT EPHA6 rs4857055 C > T polymorphism associates with hypertension through triglyceride and LDL particle size in the Korean population. 29208002 2017
dbSNP: rs258132
rs258132
Entrez Id: 5066
Gene Symbol: PAM
PAM
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		T 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs382964
rs382964
Entrez Id: 5066
Gene Symbol: PAM
PAM
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		T 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs401114
rs401114
Entrez Id: 5066
Gene Symbol: PAM
PAM
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		T 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs458256
rs458256
Entrez Id: 5066
Gene Symbol: PAM
PAM
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		G 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017