rs12701204
×
Entrez Id:
5137
Gene Symbol:
PDE1C
PDE1C
Adolescent idiopathic scoliosis
0.700
GeneticVariation
GWASCAT
The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.
30019117
2018
rs10239506
×
Entrez Id:
5137
Gene Symbol:
PDE1C
PDE1C
Arthritis, Gouty
0.700
GeneticVariation
GWASCAT
Gout and type 2 diabetes have a mutual inter-dependent effect on genetic risk factors and higher incidences.
22179738
2012
rs34173
PDE1C;PPP1R17
Aspartate aminotransferase measurement
0.700
GeneticVariation
GWASCAT
Biomarker and Genomic Risk Factors for Liver Function Test Abnormality in Hazardous Drinkers.
30589442
2019
rs215702
×
Entrez Id:
5137
Gene Symbol:
PDE1C
PDE1C
Asthenozoospermia
0.010
GeneticVariation
BEFREE
In addition, positive associations were observed between asthenozoospermia and rs215702 in LSM5 (P = 0.0016, OR = 1.479, 95% CI: 1.075-2.033) and between oligoasthenozoospermia and rs2477686 in PEX10 (P = 0.0011, OR = 2.935, 95% CI: 1.492-5.775).
27232852
2018
rs17161076
×
Entrez Id:
5137
Gene Symbol:
PDE1C
PDE1C
Body mass index
A
0.700
GeneticVariation
GWASCAT
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
26426971
2015
rs215607
×
Entrez Id:
5137
Gene Symbol:
PDE1C
PDE1C
Body mass index
G
0.700
GeneticVariation
GWASCAT
A Large Multiethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci.
30108127
2018
rs215607
×
Entrez Id:
5137
Gene Symbol:
PDE1C
PDE1C
Body mass index
A
0.700
GeneticVariation
GWASCAT
Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.
30239722
2019
rs215614
×
Entrez Id:
5137
Gene Symbol:
PDE1C
PDE1C
Body mass index
A
0.700
GeneticVariation
GWASCAT
Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.
30239722
2019
rs215634
×
Entrez Id:
5137
Gene Symbol:
PDE1C
PDE1C
Body mass index
0.700
GeneticVariation
GWASCAT
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
30595370
2019
rs7779181
×
Entrez Id:
5137
Gene Symbol:
PDE1C
PDE1C
Body mass index
C
0.700
GeneticVariation
GWASCAT
Genome-wide association study identifies 112 new loci for body mass index in the Japanese population.
28892062
2017
rs775633137
×
Entrez Id:
5137
Gene Symbol:
PDE1C
PDE1C
DEAFNESS, AUTOSOMAL DOMINANT 74
0.700
GeneticVariation
UNIPROT
A dominant variant in the PDE1C gene is associated with nonsyndromic hearing loss.
29860631
2018
rs7785659
×
Entrez Id:
5137
Gene Symbol:
PDE1C
PDE1C
Degenerative polyarthritis
0.700
GeneticVariation
GWASDB
Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.
22763110
2012
rs2270221
×
Entrez Id:
5137
Gene Symbol:
PDE1C
PDE1C
Endometriosis
A
0.800
GeneticVariation
GWASDB
Genome-wide association study link novel loci to endometriosis.
23472165
2013
rs2270221
×
Entrez Id:
5137
Gene Symbol:
PDE1C
PDE1C
Endometriosis
A
0.800
GeneticVariation
GWASCAT
Genome-wide association study link novel loci to endometriosis.
23472165
2013
rs10237735
×
Entrez Id:
5137
Gene Symbol:
PDE1C
PDE1C
Fatty acid measurement
T
0.700
GeneticVariation
GWASCAT
Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.
23362303
2013
rs10239506
×
Entrez Id:
5137
Gene Symbol:
PDE1C
PDE1C
Gout
0.700
GeneticVariation
GWASCAT
Gout and type 2 diabetes have a mutual inter-dependent effect on genetic risk factors and higher incidences.
22179738
2012
rs62458065
×
Entrez Id:
5137
Gene Symbol:
PDE1C
PDE1C
Homovanillic acid measurement
T
0.700
GeneticVariation
GWASCAT
Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.
23319000
2014
rs10236197
×
Entrez Id:
5137
Gene Symbol:
PDE1C
PDE1C
Intelligence
T
0.700
GeneticVariation
GWASCAT
Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence.
28530673
2017
rs10236197
×
Entrez Id:
5137
Gene Symbol:
PDE1C
PDE1C
Intelligence
T
0.700
GeneticVariation
GWASCAT
A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.
29326435
2019
rs10236197
×
Entrez Id:
5137
Gene Symbol:
PDE1C
PDE1C
Intelligence
T
0.700
GeneticVariation
GWASCAT
Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals.
29520040
2019
rs215600
×
Entrez Id:
5137
Gene Symbol:
PDE1C
PDE1C
Intelligence
0.700
GeneticVariation
GWASCAT
Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.
29186694
2017
rs9648380
×
Entrez Id:
5137
Gene Symbol:
PDE1C
PDE1C
Intelligence
A
0.700
GeneticVariation
GWASCAT
A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.
29326435
2019
rs9771228
×
Entrez Id:
5137
Gene Symbol:
PDE1C
PDE1C
Intelligence
0.700
GeneticVariation
GWASCAT
Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.
29186694
2017
rs7798739
×
Entrez Id:
5137
Gene Symbol:
PDE1C
PDE1C
mathematical ability
A
0.700
GeneticVariation
GWASCAT
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.
30038396
2018
rs215605
×
Entrez Id:
5137
Gene Symbol:
PDE1C
PDE1C
melanoma
0.010
GeneticVariation
BEFREE
The SNPs rs215605 in the PDE1C gene and rs6265 in the BDNF gene significantly interacted with smoking status on melanoma risk (interaction P = 0.005 and P = 0.003 respectively).
27344179
2016