PDE1C, phosphodiesterase 1C, 5137

N. diseases: 41; N. variants: 57
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2270221
rs2270221
Entrez Id: 5137
Gene Symbol: PDE1C
PDE1C
CUI: C0014175
Disease:
Endometriosis 		A 0.800 GeneticVariation GWASDB Genome-wide association study link novel loci to endometriosis. 23472165 2013
dbSNP: rs2270221
rs2270221
Entrez Id: 5137
Gene Symbol: PDE1C
PDE1C
CUI: C0014175
Disease:
Endometriosis 		A 0.800 GeneticVariation GWASCAT Genome-wide association study link novel loci to endometriosis. 23472165 2013
dbSNP: rs1014242
rs1014242
Entrez Id: 5137
Gene Symbol: PDE1C
PDE1C
CUI: C1519383
Disease:
Smoking Behaviors 		0.700 GeneticVariation GWASDB Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. 20418888 2010
dbSNP: rs10226228
rs10226228
Entrez Id: 5137
Gene Symbol: PDE1C
PDE1C
CUI: C1519383
Disease:
Smoking Behaviors 		0.700 GeneticVariation GWASDB Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. 20418888 2010
dbSNP: rs10236197
rs10236197
Entrez Id: 5137
Gene Symbol: PDE1C
PDE1C
CUI: C0021704
Disease:
Intelligence 		T 0.700 GeneticVariation GWASCAT Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence. 28530673 2017
dbSNP: rs10236197
rs10236197
Entrez Id: 5137
Gene Symbol: PDE1C
PDE1C
CUI: C0021704
Disease:
Intelligence 		T 0.700 GeneticVariation GWASCAT A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence. 29326435 2019
dbSNP: rs10236197
rs10236197
Entrez Id: 5137
Gene Symbol: PDE1C
PDE1C
CUI: C0021704
Disease:
Intelligence 		T 0.700 GeneticVariation GWASCAT Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals. 29520040 2019
dbSNP: rs10236197
rs10236197
Entrez Id: 5137
Gene Symbol: PDE1C
PDE1C
CUI: C1519383
Disease:
Smoking Behaviors 		0.700 GeneticVariation GWASDB Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. 20418888 2010
dbSNP: rs10237735
rs10237735
Entrez Id: 5137
Gene Symbol: PDE1C
PDE1C
CUI: C1281901
Disease:
Fatty acid measurement 		T 0.700 GeneticVariation GWASCAT Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. 23362303 2013
dbSNP: rs10237735
rs10237735
Entrez Id: 5137
Gene Symbol: PDE1C
PDE1C
CUI: C0202177
Disease:
Phospholipid measurement 		T 0.700 GeneticVariation GWASDB Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. 23362303 2013
dbSNP: rs10239506
rs10239506
Entrez Id: 5137
Gene Symbol: PDE1C
PDE1C
CUI: C0003868
Disease:
Arthritis, Gouty 		0.700 GeneticVariation GWASCAT Gout and type 2 diabetes have a mutual inter-dependent effect on genetic risk factors and higher incidences. 22179738 2012
dbSNP: rs10239506
rs10239506
Entrez Id: 5137
Gene Symbol: PDE1C
PDE1C
CUI: C0018099
Disease:
Gout 		0.700 GeneticVariation GWASCAT Gout and type 2 diabetes have a mutual inter-dependent effect on genetic risk factors and higher incidences. 22179738 2012
dbSNP: rs10259431
rs10259431
Entrez Id: 5137
Gene Symbol: PDE1C
PDE1C
CUI: C1519383
Disease:
Smoking Behaviors 		0.700 GeneticVariation GWASDB Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. 20418888 2010
dbSNP: rs10264177
rs10264177
Entrez Id: 5137
Gene Symbol: PDE1C
PDE1C
CUI: C1519383
Disease:
Smoking Behaviors 		0.700 GeneticVariation GWASDB Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. 20418888 2010
dbSNP: rs10951331
rs10951331
Entrez Id: 5137
Gene Symbol: PDE1C
PDE1C
CUI: C1519383
Disease:
Smoking Behaviors 		0.700 GeneticVariation GWASDB Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. 20418888 2010
dbSNP: rs12531858
rs12531858
Entrez Id: 5137
Gene Symbol: PDE1C
PDE1C
CUI: C1519383
Disease:
Smoking Behaviors 		0.700 GeneticVariation GWASDB Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. 20418888 2010
dbSNP: rs12540232
rs12540232
Entrez Id: 5137
Gene Symbol: PDE1C
PDE1C
CUI: C1519383
Disease:
Smoking Behaviors 		0.700 GeneticVariation GWASDB Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. 20418888 2010
dbSNP: rs12701204
rs12701204
Entrez Id: 5137
Gene Symbol: PDE1C
PDE1C
CUI: C0410702
Disease:
Adolescent idiopathic scoliosis 		0.700 GeneticVariation GWASCAT The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease. 30019117 2018
dbSNP: rs12701204
rs12701204
Entrez Id: 5137
Gene Symbol: PDE1C
PDE1C
CUI: C1837461
Disease:
SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3 		0.700 GeneticVariation GWASCAT The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease. 30019117 2018
dbSNP: rs1450869
rs1450869
Entrez Id: 5137
Gene Symbol: PDE1C
PDE1C
CUI: C1519383
Disease:
Smoking Behaviors 		0.700 GeneticVariation GWASDB Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. 20418888 2010
dbSNP: rs1450870
rs1450870
Entrez Id: 5137
Gene Symbol: PDE1C
PDE1C
CUI: C1519383
Disease:
Smoking Behaviors 		0.700 GeneticVariation GWASDB Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. 20418888 2010
dbSNP: rs1476765
rs1476765
Entrez Id: 5137
Gene Symbol: PDE1C
PDE1C
CUI: C1519383
Disease:
Smoking Behaviors 		0.700 GeneticVariation GWASDB Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. 20418888 2010
dbSNP: rs17161076
rs17161076
Entrez Id: 5137
Gene Symbol: PDE1C
PDE1C
CUI: C1305855
Disease:
Body mass index 		A 0.700 GeneticVariation GWASCAT The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. 26426971 2015
dbSNP: rs215596
rs215596
Entrez Id: 5137
Gene Symbol: PDE1C
PDE1C
CUI: C1519383
Disease:
Smoking Behaviors 		0.700 GeneticVariation GWASDB Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. 20418888 2010
dbSNP: rs215599
rs215599
Entrez Id: 5137
Gene Symbol: PDE1C
PDE1C
CUI: C1519383
Disease:
Smoking Behaviors 		0.700 GeneticVariation GWASDB Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. 20418888 2010