PHB, prohibitin, 5245

N. diseases: 177; N. variants: 8
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs55714120
rs55714120
Entrez Id: 5245
Gene Symbol: PHB
PHB
CUI: C0871470
Disease:
Systolic Pressure 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs55714120
rs55714120
Entrez Id: 5245
Gene Symbol: PHB
PHB
CUI: C0023508
Disease:
White Blood Cell Count procedure 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs2898883
rs2898883
Entrez Id: 5245
Gene Symbol: PHB
PHB
CUI: C0008074
Disease:
Child Development Disorders, Pervasive 		0.700 GeneticVariation GWASCAT ASD restricted and repetitive behaviors associated at 17q21.33: genes prioritized by expression in fetal brains. 28533516 2018
dbSNP: rs2898883
rs2898883
Entrez Id: 5245
Gene Symbol: PHB
PHB
CUI: C1510586
Disease:
Autism Spectrum Disorders 		0.700 GeneticVariation GWASCAT ASD restricted and repetitive behaviors associated at 17q21.33: genes prioritized by expression in fetal brains. 28533516 2018
dbSNP: rs7502499
rs7502499
Entrez Id: 5245
Gene Symbol: PHB
PHB
CUI: C1956346
Disease:
Coronary Artery Disease 		A 0.700 GeneticVariation GWASCAT Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease. 29212778 2018
dbSNP: rs7502499
rs7502499
Entrez Id: 5245
Gene Symbol: PHB
PHB
CUI: C0006826
Disease:
Malignant Neoplasms 		G 0.700 GeneticVariation GWASCAT Cancer risk susceptibility loci in a Swedish population. 29299148 2017
dbSNP: rs112294663
rs112294663
Entrez Id: 5245
Gene Symbol: PHB
PHB
CUI: C3469522
Disease:
BREAST CANCER, SUSCEPTIBILITY TO 		A 0.700 SusceptibilityMutation CLINVAR
dbSNP: rs121918372
rs121918372
Entrez Id: 5245
Gene Symbol: PHB
PHB
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.700 GeneticVariation UNIPROT
dbSNP: rs121918373
rs121918373
Entrez Id: 5245
Gene Symbol: PHB
PHB
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.700 GeneticVariation UNIPROT
dbSNP: rs6917
rs6917
Entrez Id: 5245
Gene Symbol: PHB
PHB
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.010 GeneticVariation BEFREE Four SNPs [rs3218550 (XRCC2), rs6</span>917 (PHB), rs1801516 (ATM), and rs13689 (CDH1)] were significantly associated with risk of breast cancer. 29433565 2018
dbSNP: rs6917
rs6917
Entrez Id: 5245
Gene Symbol: PHB
PHB
CUI: C0678222
Disease:
Breast Carcinoma 		0.010 GeneticVariation BEFREE Four SNPs [rs3218550 (XRCC2), rs6</span>917 (PHB), rs1801516 (ATM), and rs13689 (CDH1)] were significantly associated with risk of breast cancer. 29433565 2018
dbSNP: rs770849761
rs770849761
Entrez Id: 5245
Gene Symbol: PHB
PHB
CUI: C0699791
Disease:
Stomach Carcinoma 		0.010 GeneticVariation BEFREE Association of 758 G/A polymorphism of 3'untranslated region of prohibitin with risk of gastric cancer. 28294412 2018
dbSNP: rs770849761
rs770849761
Entrez Id: 5245
Gene Symbol: PHB
PHB
CUI: C0024623
Disease:
Malignant neoplasm of stomach 		0.010 GeneticVariation BEFREE Association of 758 G/A polymorphism of 3'untranslated region of prohibitin with risk of gastric cancer. 28294412 2018
dbSNP: rs6917
rs6917
Entrez Id: 5245
Gene Symbol: PHB
PHB
CUI: C0024623
Disease:
Malignant neoplasm of stomach 		0.010 GeneticVariation BEFREE Here, we evaluated whether the PHB copy number and the rs6917 polymorphism affect its expression in gastric cancer. 24879411 2014
dbSNP: rs6917
rs6917
Entrez Id: 5245
Gene Symbol: PHB
PHB
CUI: C0699791
Disease:
Stomach Carcinoma 		0.010 GeneticVariation BEFREE Here, we evaluated whether the PHB copy number and the rs6917 polymorphism affect its expression in gastric cancer. 24879411 2014
dbSNP: rs6917
rs6917
Entrez Id: 5245
Gene Symbol: PHB
PHB
CUI: C0919267
Disease:
ovarian neoplasm 		0.010 GeneticVariation BEFREE To evaluate the potential role of genetic variants within PHB and MTHFR in breast and ovarian cancer risk, 4102 BRCA1 and 2093 BRCA2 mutation carriers, and 6211 BRCA1 and 2902 BRCA2 carriers from the Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (CIMBA) were genotyped for the PHB 1630 C>T (rs6917) polymorphism and the MTHFR 677 C>T (rs1801133) polymorphism, respectively. 22669161 2012
dbSNP: rs6917
rs6917
Entrez Id: 5245
Gene Symbol: PHB
PHB
CUI: C4721610
Disease:
Carcinoma, Ovarian Epithelial 		0.010 GeneticVariation BEFREE To evaluate the potential role of genetic variants within PHB and MTHFR in breast and ovarian cancer risk, 4102 BRCA1 and 2093 BRCA2 mutation carriers, and 6211 BRCA1 and 2902 BRCA2 carriers from the Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (CIMBA) were genotyped for the PHB 1630 C>T (rs6917) polymorphism and the MTHFR 677 C>T (rs1801133) polymorphism, respectively. 22669161 2012
dbSNP: rs6917
rs6917
Entrez Id: 5245
Gene Symbol: PHB
PHB
CUI: C1140680
Disease:
Malignant neoplasm of ovary 		0.010 GeneticVariation BEFREE To evaluate the potential role of genetic variants within PHB and MTHFR in breast and ovarian cancer risk, 4102 BRCA1 and 2093 BRCA2 mutation carriers, and 6211 BRCA1 and 2902 BRCA2 carriers from the Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (CIMBA) were genotyped for the PHB 1630 C>T (rs6917) polymorphism and the MTHFR 677 C>T (rs1801133) polymorphism, respectively. 22669161 2012