|
rs12436
|
SERPINE2
|
Body Height
|
|
0.700 |
GeneticVariation |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
rs7576030
|
SERPINE2
|
Body Height
|
|
0.700 |
GeneticVariation |
GWASCAT |
Characterizing rare and low-frequency height-associated variants in the Japanese population.
|
31562340 |
2019 |
|
rs13412535
|
SERPINE2
|
Blood Protein Measurement
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genomic atlas of the human plasma proteome.
|
29875488 |
2018 |
|
rs68066031
|
SERPINE2
|
Blood Protein Measurement
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genomic atlas of the human plasma proteome.
|
29875488 |
2018 |
|
rs68066031
|
SERPINE2
|
Blood Protein Measurement
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Co-regulatory networks of human serum proteins link genetics to disease.
|
30072576 |
2018 |
|
rs861442
|
SERPINE2
|
Blood Protein Measurement
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genomic atlas of the human plasma proteome.
|
29875488 |
2018 |
|
rs863957
|
SERPINE2
|
Blood Protein Measurement
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Genomic atlas of the human plasma proteome.
|
29875488 |
2018 |
|
rs13412535
|
SERPINE2
|
Stem Cell Factor Measurement
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.
|
27989323 |
2017 |
|
rs13412535
|
SERPINE2
|
Soluble Interleukin 6 Receptor Measurement
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.
|
27989323 |
2017 |
|
rs13412535
|
SERPINE2
|
Interleukin 2 Measurement
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.
|
27989323 |
2017 |
|
rs13412535
|
SERPINE2
|
Platelet mean volume determination (procedure)
|
A |
0.700 |
GeneticVariation |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
|
rs16865421
|
SERPINE2
|
Chronic Obstructive Airway Disease
|
|
0.020 |
GeneticVariation |
BEFREE |
Polymorphisms of rs16865421-AG carried by the Uygur population may be protective against COPD.
|
31215134 |
2019 |
|
rs729631
|
SERPINE2
|
Chronic Obstructive Airway Disease
|
|
0.020 |
GeneticVariation |
BEFREE |
Two SNPs (rs729631 and rs975278), which are in strong linkage disequilibrium (LD) and locate in block 1 on the LD map of our samples, showed significant association both with the risk of COPD and decline in baseline lung function after Bonferroni correction (P < 0.05).
|
21611750 |
2012 |
|
rs16865421
|
SERPINE2
|
Chronic Obstructive Airway Disease
|
|
0.020 |
GeneticVariation |
BEFREE |
In haplotype analysis, the GACC haplotype carrying the polymorphic allele at the rs16865421 was associated with a significantly decreased risk of COPD when compared to the AACC haplotype (adjusted OR=0.58, 95% CI=0.38-0.89, P=0.01), and this effect was evident in younger individuals (adjusted OR=0.30, 95% CI=0.14-0.64, P=0.002).
|
19949669 |
2009 |
|
rs729631
|
SERPINE2
|
Chronic Obstructive Airway Disease
|
|
0.020 |
GeneticVariation |
BEFREE |
To test this hypothesis, the association of four SERPINE2 single nucleotide polymorphisms (SNPs; rs16865421A>G, rs7583463A>C, rs729631C>G, and rs6734100C>G) with the risk of COPD was investigated in a case-control study of 311 COPD patients and 386 controls.
|
19949669 |
2009 |
|
rs3795879
|
SERPINE2
|
Chronic Obstructive Airway Disease
|
|
0.010 |
GeneticVariation |
BEFREE |
The results suggest that the rs3795879 polymorphism of SERPINE2 is not a risk factor for COPD.
|
26214473 |
2015 |
|
rs975278
|
SERPINE2
|
Chronic Obstructive Airway Disease
|
|
0.010 |
GeneticVariation |
BEFREE |
Two SNPs (rs729631 and rs975278), which are in strong linkage disequilibrium (LD) and locate in block 1 on the LD map of our samples, showed significant association both with the risk of COPD and decline in baseline lung function after Bonferroni correction (P < 0.05).
|
21611750 |
2012 |
|
rs729631
|
SERPINE2
|
Pulmonary Emphysema
|
|
0.010 |
GeneticVariation |
BEFREE |
A haplotype consisting of variant alleles of both rs729631 and rs840088 SNPs was found to pose an almost four-fold risk for overall panlobular (OR 3.72, 95% CI 1.56-8.90) and subnormal (OR 3.98, 95% CI 1.55-10.20) emphysema.
|
22145704 |
2011 |
|
rs729631
|
SERPINE2
|
Panacinar Emphysema
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs729631 SNP showed a significant association with panlobular emphysema (p = 0.003).
|
22145704 |
2011 |
|
rs840088
|
SERPINE2
|
Pulmonary Emphysema
|
|
0.010 |
GeneticVariation |
BEFREE |
A haplotype consisting of variant alleles of both rs729631 and rs840088 SNPs was found to pose an almost four-fold risk for overall panlobular (OR 3.72, 95% CI 1.56-8.90) and subnormal (OR 3.98, 95% CI 1.55-10.20) emphysema.
|
22145704 |
2011 |
|
rs975278
|
SERPINE2
|
Pulmonary Emphysema
|
|
0.010 |
GeneticVariation |
BEFREE |
Among the 12 examined SNPs, only rs975278 in the SERPINE2 gene was positively associated with emphysema.
|
21067581 |
2010 |
|
rs6734100
|
SERPINE2
|
Chronic Obstructive Airway Disease
|
|
0.010 |
GeneticVariation |
BEFREE |
To test this hypothesis, the association of four SERPINE2 single nucleotide polymorphisms (SNPs; rs16865421A>G, rs7583463A>C, rs729631C>G, and rs6734100C>G) with the risk of COPD was investigated in a case-control study of 311 COPD patients and 386 controls.
|
19949669 |
2009 |