SHC3, SHC adaptor protein 3, 53358

N. diseases: 72; N. variants: 10
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12519
rs12519
Entrez Id: 53358
Gene Symbol: SHC3
SHC3
CUI: C0028043
Disease:
Nicotine Dependence
0.010 GeneticVariation BEFREE Haplotype analysis revealed that the haplotypes A-C-T-A-T-A of rs12519-rs3750399-rs4877042-rs2297313-rs1547696-rs1331188, with a frequency of 27.8 and 17.6%, and C-T-A-G-T of rs3750399-rs4877042-rs2297313-rs3818668-rs1547696, at a frequency of 44.7 and 30.6% in the AA and Combined samples, respectively, were significantly inversely associated with the ND measures. 17179996 2007
dbSNP: rs1331188
rs1331188
Entrez Id: 53358
Gene Symbol: SHC3
SHC3
CUI: C0028043
Disease:
Nicotine Dependence
0.010 GeneticVariation BEFREE In the EA sample, another haplotype with a frequency of 10.6%, A-G-T-G of rs1331188-rs1556384-rs4534195-rs1411836, showed a significant inverse association with ND measures. 17179996 2007
dbSNP: rs1411836
rs1411836
Entrez Id: 53358
Gene Symbol: SHC3
SHC3
CUI: C0028043
Disease:
Nicotine Dependence
0.010 GeneticVariation BEFREE In the EA sample, another haplotype with a frequency of 10.6%, A-G-T-G of rs1331188-rs1556384-rs4534195-rs1411836, showed a significant inverse association with ND measures. 17179996 2007
dbSNP: rs1547696
rs1547696
Entrez Id: 53358
Gene Symbol: SHC3
SHC3
CUI: C0028043
Disease:
Nicotine Dependence
0.010 GeneticVariation BEFREE Haplotype analysis revealed that the haplotypes A-C-T-A-T-A of rs12519-rs3750399-rs4877042-rs2297313-rs1547696-rs1331188, with a frequency of 27.8 and 17.6%, and C-T-A-G-T of rs3750399-rs4877042-rs2297313-rs3818668-rs1547696, at a frequency of 44.7 and 30.6% in the AA and Combined samples, respectively, were significantly inversely associated with the ND measures. 17179996 2007
dbSNP: rs1556384
rs1556384
Entrez Id: 53358
Gene Symbol: SHC3
SHC3
CUI: C0028043
Disease:
Nicotine Dependence
0.010 GeneticVariation BEFREE In the EA sample, another haplotype with a frequency of 10.6%, A-G-T-G of rs1331188-rs1556384-rs4534195-rs1411836, showed a significant inverse association with ND measures. 17179996 2007
dbSNP: rs2297313
rs2297313
Entrez Id: 53358
Gene Symbol: SHC3
SHC3
CUI: C0028043
Disease:
Nicotine Dependence
0.010 GeneticVariation BEFREE Haplotype analysis revealed that the haplotypes A-C-T-A-T-A of rs12519-rs3750399-rs4877042-rs2297313-rs1547696-rs1331188, with a frequency of 27.8 and 17.6%, and C-T-A-G-T of rs3750399-rs4877042-rs2297313-rs3818668-rs1547696, at a frequency of 44.7 and 30.6% in the AA and Combined samples, respectively, were significantly inversely associated with the ND measures. 17179996 2007
dbSNP: rs3750399
rs3750399
Entrez Id: 53358
Gene Symbol: SHC3
SHC3
CUI: C0028043
Disease:
Nicotine Dependence
0.010 GeneticVariation BEFREE Haplotype analysis revealed that the haplotypes A-C-T-A-T-A of rs12519-rs3750399-rs4877042-rs2297313-rs1547696-rs1331188, with a frequency of 27.8 and 17.6%, and C-T-A-G-T of rs3750399-rs4877042-rs2297313-rs3818668-rs1547696, at a frequency of 44.7 and 30.6% in the AA and Combined samples, respectively, were significantly inversely associated with the ND measures. 17179996 2007
dbSNP: rs3818668
rs3818668
Entrez Id: 53358
Gene Symbol: SHC3
SHC3
CUI: C0028043
Disease:
Nicotine Dependence
0.010 GeneticVariation BEFREE Haplotype analysis revealed that the haplotypes A-C-T-A-T-A of rs12519-rs3750399-rs4877042-rs2297313-rs1547696-rs1331188, with a frequency of 27.8 and 17.6%, and C-T-A-G-T of rs3750399-rs4877042-rs2297313-rs3818668-rs1547696, at a frequency of 44.7 and 30.6% in the AA and Combined samples, respectively, were significantly inversely associated with the ND measures. 17179996 2007
dbSNP: rs4534195
rs4534195
Entrez Id: 53358
Gene Symbol: SHC3
SHC3
CUI: C0028043
Disease:
Nicotine Dependence
0.010 GeneticVariation BEFREE In the EA sample, another haplotype with a frequency of 10.6%, A-G-T-G of rs1331188-rs1556384-rs4534195-rs1411836, showed a significant inverse association with ND measures. 17179996 2007
dbSNP: rs4877042
rs4877042
Entrez Id: 53358
Gene Symbol: SHC3
SHC3
CUI: C0028043
Disease:
Nicotine Dependence
0.010 GeneticVariation BEFREE Haplotype analysis revealed that the haplotypes A-C-T-A-T-A of rs12519-rs3750399-rs4877042-rs2297313-rs1547696-rs1331188, with a frequency of 27.8 and 17.6%, and C-T-A-G-T of rs3750399-rs4877042-rs2297313-rs3818668-rs1547696, at a frequency of 44.7 and 30.6% in the AA and Combined samples, respectively, were significantly inversely associated with the ND measures. 17179996 2007