TLR9, toll like receptor 9, 54106

N. diseases: 457; N. variants: 11
Disease: Primary malignant neoplasm ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs187084
rs187084
Entrez Id: 54106
Gene Symbol: TLR9
TLR9
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.030 GeneticVariation BEFREE Stage-wise analysis revealed TLR9 rs187084 and rs352140 to be associated with early-stage cancer. 31278284 2019
dbSNP: rs187084
rs187084
Entrez Id: 54106
Gene Symbol: TLR9
TLR9
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.030 GeneticVariation BEFREE In conclusion, our results suggest that the rs187084 polymorphism may be associated with an elevated cancer risk, whereas polymorphisms of rs352140 and rs5743836 may play protective roles in the development of breast and digestive system cancers, respectively. 25339018 2014
dbSNP: rs187084
rs187084
Entrez Id: 54106
Gene Symbol: TLR9
TLR9
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.030 GeneticVariation BEFREE However, no significantly increased cancer risk was detected to be associated with rs187084</span> and rs5743836 either the overall or subgroup estimation. 23990988 2013
dbSNP: rs352140
rs352140
Entrez Id: 54106
Gene Symbol: TLR9
TLR9
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.020 GeneticVariation BEFREE Stage-wise analysis revealed TLR9 rs187084 and rs352140 to be associated with early-stage cancer. 31278284 2019
dbSNP: rs5743836
rs5743836
Entrez Id: 54106
Gene Symbol: TLR9
TLR9
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.020 GeneticVariation BEFREE In conclusion, our results suggest that the rs187084 polymorphism may be associated with an elevated cancer risk, whereas polymorphisms of rs352140 and rs5743836 may play protective roles in the development of breast and digestive system cancers, respectively. 25339018 2014
dbSNP: rs352140
rs352140
Entrez Id: 54106
Gene Symbol: TLR9
TLR9
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.020 GeneticVariation BEFREE Our meta-analysis indicated that rs352140 was associated with an increased cancer risk, especially in Caucasian. 23990988 2013
dbSNP: rs5743836
rs5743836
Entrez Id: 54106
Gene Symbol: TLR9
TLR9
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.020 GeneticVariation BEFREE However, no significantly increased cancer risk was detected to be associated with rs187084 and rs5743836 either the overall or subgroup estimation. 23990988 2013