Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs9658111
rs9658111
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0200635
Disease:
Lymphocyte Count measurement
C 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs2016520
rs2016520
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0028754
Disease:
Obesity
0.060 GeneticVariation BEFREE C-C haplotype, constructed from rs2016520 and rs9794 alleles, showed a significant protective effect for both abnormal weight and abdominal obesity. 26073637 2016
dbSNP: rs2016520
rs2016520
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0028754
Disease:
Obesity
0.060 GeneticVariation BEFREE Polymorphism of rs2016520 in gene PPARD has been associated with lipid metabolism, obesity, metabolic syndrome and type 2 diabetes mellitus (T2DM). 26915488 2016
dbSNP: rs2016520
rs2016520
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.040 GeneticVariation BEFREE Polymorphism of rs2016520 in gene PPARD has been associated with lipid metabolism, obesity, metabolic syndrome and type 2 diabetes mellitus (T2DM). 26915488 2016
dbSNP: rs2016520
rs2016520
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0085580
Disease:
Essential Hypertension
0.010 GeneticVariation BEFREE We also found a potential SNP-SNP interaction between rs2016520 and rs9794; subjects with TC or CC of rs2016520 and CG or GG of rs9794 genotype have the lowest EH ris</span>k, compared to subjects with TT of rs2016520 and CC of rs9794 genotype; OR (95%CI) was 0.32 (0.23-0.62) after covariate adjustment. 26613934 2016
dbSNP: rs9794
rs9794
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0085580
Disease:
Essential Hypertension
0.010 GeneticVariation BEFREE We also found a potential SNP-SNP interaction between rs2016520 and rs979</span>4</span>; subjects with TC or CC of rs2016520 and CG or GG of rs9794 genotype have the lowest EH risk, compared to subjects with TT of rs2016520 and CC of rs9794 genotype; OR (95%CI) was 0.32 (0.23-0.62) after covariate adjustment. 26613934 2016
dbSNP: rs9794
rs9794
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0028754
Disease:
Obesity
0.010 GeneticVariation BEFREE C-C haplotype, constructed from rs2016520 and rs9794 alleles, showed a significant protective effect for both abnormal weight and abdominal obesity. 26073637 2016
dbSNP: rs36018387
rs36018387
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0005890
Disease:
Body Height
T 0.700 GeneticVariation GWASCAT Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. 28552196 2017
dbSNP: rs2016520
rs2016520
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0028754
Disease:
Obesity
0.060 GeneticVariation BEFREE Accumulated evidence suggests that the polymorphism rs2016520 in PPARD is associated with lipid metabolism, obesity, metabolic syndrome, and type 2 diabetes mellitus. 28128413 2017
dbSNP: rs2016520
rs2016520
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.040 GeneticVariation BEFREE Accumulated evidence suggests that the polymorphism rs2016520 in PPARD is associated with lipid metabolism, obesity, metabolic syndrome, and type 2 diabetes mellitus. 28128413 2017
dbSNP: rs2016520
rs2016520
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0009402
Disease:
Colorectal Carcinoma
0.020 GeneticVariation BEFREE In conclusion, for the first time, the association between the +294T/C (rs2016520) polymorphism and colorectal cancer has been studied in Mexican patients. 28128413 2017
dbSNP: rs2016520
rs2016520
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0007222
Disease:
Cardiovascular Diseases
0.010 GeneticVariation BEFREE The minor allele of rs2016520 and rs9794 in PPAR-δ and interaction between rs2016520 and non-smoking were associated with decreased risk of CVD. 28287878 2017
dbSNP: rs2016520
rs2016520
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C4722085
Disease:
Malignant neoplasm of colon and/or rectum
0.010 GeneticVariation BEFREE In conclusion, for the first time, the association between the +294T/C (rs2016520) polymorphism and colorectal cancer has been studied in Mexican patients. 28128413 2017
dbSNP: rs9794
rs9794
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0007222
Disease:
Cardiovascular Diseases
0.010 GeneticVariation BEFREE The minor allele of rs2016520 and rs9794 in PPAR-δ and interaction between rs2016520 and non-smoking were associated with decreased risk of CVD. 28287878 2017
dbSNP: rs7770619
rs7770619
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.010 GeneticVariation BEFREE Glucose levels and the rs7770619 are significantly associated in individuals with normal fasting glucose, and a trend towards an association between glucose levels and rs7770619 is also observed in individuals with impaired fasting glucose or type 2 diabetes. 29776318 2018
dbSNP: rs7770619
rs7770619
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0020538
Disease:
Hypertensive disease
0.010 GeneticVariation BEFREE This is a new finding that the PPARD rs7770619 C>T SNP is a novel candidate variant for HTN based on the association between PPARD and plasma MDA in a Korean population. 29914579 2018
dbSNP: rs2395622
rs2395622
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0871470
Disease:
Systolic Pressure
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs9470004
rs9470004
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0005890
Disease:
Body Height
0.700 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584 2019
dbSNP: rs9658134
rs9658134
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0005890
Disease:
Body Height
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs2016520
rs2016520
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0009402
Disease:
Colorectal Carcinoma
0.020 GeneticVariation BEFREE In this study, whether the intratumoral heterogeneity of polymorphism of PPARD-87 T>C (rs2016520) existed and its influence in CRC were investigated. 30868900 2019
dbSNP: rs3734254
rs3734254
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0278510
Disease:
Childhood Medulloblastoma
0.010 GeneticVariation BEFREE Of the eight SNPs identified, PPARα (rs6008197), PPARγ (rs13306747), and PPARδ (rs3734254) were most significantly associated with long-term changes in general intellectual functioning in medulloblastoma survivors. 30607709 2019
dbSNP: rs3734254
rs3734254
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0278876
Disease:
Adult Medulloblastoma
0.010 GeneticVariation BEFREE Of the eight SNPs identified, PPARα (rs6008197), PPARγ (rs13306747), and PPARδ (rs3734254) were most significantly associated with long-term changes in general intellectual functioning in medulloblastoma survivors. 30607709 2019
dbSNP: rs3734254
rs3734254
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0025149
Disease:
Medulloblastoma
0.010 GeneticVariation BEFREE Of the eight SNPs identified, PPARα (rs6008197), PPARγ (rs13306747), and PPARδ (rs3734254) were most significantly associated with long-term changes in general intellectual functioning in medulloblastoma survivors. 30607709 2019
dbSNP: rs3777744
rs3777744
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C1956346
Disease:
Coronary Artery Disease
0.010 GeneticVariation BEFREE <b>Conclusions</b>: Our study indicates a significant association between the G-alleles of PPARD rs3777744 and rs3798343 and a decreased CAD risk. 30429241 2019
dbSNP: rs3798343
rs3798343
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0010054
Disease:
Coronary Arteriosclerosis
0.010 GeneticVariation BEFREE The association between peroxisome proliferator-activated receptor Δ rs3777744, rs3798343, and rs6922548 and coronary artery disease. 30429241 2019