Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0009402
Disease:
Colorectal Carcinoma 		0.700 GeneticVariation UNIPROT
dbSNP: rs991177157
rs991177157
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.700 GeneticVariation UNIPROT
dbSNP: rs1309461162
rs1309461162
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0027651
Disease:
Neoplasms 		0.010 GeneticVariation BEFREE To date, the only activated allele of MYC known is T58A, the study of which led to identification of the tumor suppressor FBXW7 and its regulator USP28 as a novel therapeutic target. 24030976 2013
dbSNP: rs149680468
rs149680468
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0027651
Disease:
Neoplasms 		0.010 GeneticVariation BEFREE We identified the Arg505Cys mutation in the tumour suppressor FBXW7. 25361747 2015
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0280630
Disease:
Uterine Carcinosarcoma 		G 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0278701
Disease:
Gastric Adenocarcinoma 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0009404
Disease:
Colorectal Neoplasms 		G 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0278701
Disease:
Gastric Adenocarcinoma 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0007873
Disease:
Uterine Cervical Neoplasm 		G 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0279663
Disease:
Serous cystadenocarcinoma ovary 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0279663
Disease:
Serous cystadenocarcinoma ovary 		G 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0010606
Disease:
Adenoid Cystic Carcinoma 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0152018
Disease:
Esophageal carcinoma 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0010606
Disease:
Adenoid Cystic Carcinoma 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0025149
Disease:
Medulloblastoma 		G 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C1168401
Disease:
Squamous cell carcinoma of the head and neck 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C1458155
Disease:
Mammary Neoplasms 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0280630
Disease:
Uterine Carcinosarcoma 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0025149
Disease:
Medulloblastoma 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C1458155
Disease:
Mammary Neoplasms 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0280630
Disease:
Uterine Carcinosarcoma 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0153574
Disease:
Malignant Uterine Corpus Neoplasm 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0279663
Disease:
Serous cystadenocarcinoma ovary 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0025149
Disease:
Medulloblastoma 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016