Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0009402
Disease:
Colorectal Carcinoma 		0.700 GeneticVariation UNIPROT
dbSNP: rs991177157
rs991177157
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.700 GeneticVariation UNIPROT
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0006826
Disease:
Malignant Neoplasms 		0.010 GeneticVariation BEFREE Cancer-associated arginine mutations in the WD40 domain (R465H, R479Q and R505C) abolish both FBXW7 interaction with PAR and recruitment to DNA damage sites, causing inhibition of XRCC4 polyubiquitination and NHEJ. 30722038 2019
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.010 GeneticVariation BEFREE Cancer-associated arginine mutations in the WD40 domain (R465H, R479Q and R505C) abolish both FBXW7 interaction with PAR and recruitment to DNA damage sites, causing inhibition of XRCC4 polyubiquitination and NHEJ. 30722038 2019
dbSNP: rs149680468
rs149680468
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.010 GeneticVariation BEFREE Cancer-associated arginine mutations in the WD40 domain (R465H, R479Q and R505C) abolish both FBXW7 interaction with PAR and recruitment to DNA damage sites, causing inhibition of XRCC4 polyubiquitination and NHEJ. 30722038 2019
dbSNP: rs149680468
rs149680468
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0006826
Disease:
Malignant Neoplasms 		0.010 GeneticVariation BEFREE Cancer-associated arginine mutations in the WD40 domain (R465H, R479Q and R505C) abolish both FBXW7 interaction with PAR and recruitment to DNA damage sites, causing inhibition of XRCC4 polyubiquitination and NHEJ. 30722038 2019
dbSNP: rs7685296
rs7685296
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		T 0.700 GeneticVariation GWASCAT Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. 30054458 2018
dbSNP: rs7660590
rs7660590
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		C 0.700 GeneticVariation GWASCAT Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population. 30718926 2019
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0280630
Disease:
Uterine Carcinosarcoma 		G 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0278701
Disease:
Gastric Adenocarcinoma 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0009404
Disease:
Colorectal Neoplasms 		G 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0278701
Disease:
Gastric Adenocarcinoma 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0007873
Disease:
Uterine Cervical Neoplasm 		G 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0279663
Disease:
Serous cystadenocarcinoma ovary 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0279663
Disease:
Serous cystadenocarcinoma ovary 		G 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0010606
Disease:
Adenoid Cystic Carcinoma 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0152018
Disease:
Esophageal carcinoma 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0010606
Disease:
Adenoid Cystic Carcinoma 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0025149
Disease:
Medulloblastoma 		G 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C1168401
Disease:
Squamous cell carcinoma of the head and neck 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C1458155
Disease:
Mammary Neoplasms 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0280630
Disease:
Uterine Carcinosarcoma 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0025149
Disease:
Medulloblastoma 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
dbSNP: rs1057519895
rs1057519895
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C1458155
Disease:
Mammary Neoplasms 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016