Disease: Alzheimer's Disease ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1868402
rs1868402
Entrez Id: 5534
Gene Symbol: PPP3R1
PPP3R1
CUI: C0002395
Disease:
Alzheimer's Disease 		0.020 GeneticVariation BEFREE Single-nucleotide polymorphisms (SNPs) located in the gene encoding the regulatory subunit of the protein phosphatase 2B (PPP3R1, rs1868402) and the microtubule-associated protein tau (MAPT, rs3785883) gene were recently associated with higher cerebrospinal fluid (CSF) tau levels in samples from the Knight Alzheimer's Disease Research Center at Washington University (WU) and Alzheimer's Disease Neuroimaging Initiative (ADNI). 23727081 2014
dbSNP: rs1868402
rs1868402
Entrez Id: 5534
Gene Symbol: PPP3R1
PPP3R1
CUI: C0002395
Disease:
Alzheimer's Disease 		0.020 GeneticVariation BEFREE We show no association of rs1868402 with risk for AD or age at onset, but detected a very significant association with rate of progression of disease that is consistent in two independent series (P(combined) = 1.17 x 10(-05)). 20862329 2010