rs121918282
SCN3B;LOC105369543
Brugada Syndrome (disorder)
0.010
GeneticVariation
BEFREE
A missense mutation (L10P ) was detected in exon 1 of SCN3B, the beta 3 subunit of the cardiac sodium channel, but not in any other gene known to be associated with Brugada syndrome or in 296 controls.
20031595
2009
rs1412069210
×
Entrez Id:
55800
Gene Symbol:
SCN3B
SCN3B
Atrial Fibrillation
0.010
GeneticVariation
BEFREE
As a result, 2 novel heterozygous SCN4B mutations, p.V162G and p.I166L , were identified in 2 unrelated families with AF transmitted in an autosomal dominant pattern, respectively.
23604097
2013
rs147205617
×
Entrez Id:
55800
Gene Symbol:
SCN3B
SCN3B
Brugada Syndrome (disorder)
0.010
GeneticVariation
BEFREE
The Val110Ile mutation of SCN3B is a relatively common cause of SCN5A-negative BrS in Japan, which has a reduced sodium current because of the loss of cell surface expression of Nav1.5.
23257389
2013
rs1783901
×
Entrez Id:
55800
Gene Symbol:
SCN3B
SCN3B
Vertigo
0.010
GeneticVariation
BEFREE
Our results suggest that the SNPs r s1939012 and rs1783901 may play a potential role of gene regulation and/or epistasis in a complex etio logy of vertigo .
30300896
2018
rs587777556
×
Entrez Id:
55800
Gene Symbol:
SCN3B
SCN3B
Atrial Fibrillation
0.010
GeneticVariation
BEFREE
A novel A130V mutation was identified in a 46-year-old patient with lone AF , and the mutation was absent in 500 controls.
20558140
2010
rs121918282
SCN3B;LOC105369543
ATRIAL FIBRILLATION, FAMILIAL, 16
G
0.700
CausalMutation
CLINVAR
rs121918282
SCN3B;LOC105369543
Brugada Syndrome 7
G
0.700
GeneticVariation
CLINVAR
rs121918282
SCN3B;LOC105369543
Brugada Syndrome 7
G
0.700
CausalMutation
CLINVAR
rs147205617
×
Entrez Id:
55800
Gene Symbol:
SCN3B
SCN3B
Death in infancy
T
0.700
CausalMutation
CLINVAR
Postmortem genetic screening for the identification, verification, and reporting of genetic variants contributing to the sudden death of the young.
27435932
2016
rs587777557
×
Entrez Id:
55800
Gene Symbol:
SCN3B
SCN3B
ATRIAL FIBRILLATION, FAMILIAL, 16
G
0.700
CausalMutation
CLINVAR
rs587777558
SCN3B;LOC105369543
ATRIAL FIBRILLATION, FAMILIAL, 16
T
0.700
CausalMutation
CLINVAR
rs879253730
×
Entrez Id:
55800
Gene Symbol:
SCN3B
SCN3B
Cardiac Arrhythmia
C
0.700
CausalMutation
CLINVAR
Postmortem genetic screening for the identification, verification, and reporting of genetic variants contributing to the sudden death of the young.
27435932
2016
rs879253730
×
Entrez Id:
55800
Gene Symbol:
SCN3B
SCN3B
Electrocardiogram change
C
0.700
CausalMutation
CLINVAR
Postmortem genetic screening for the identification, verification, and reporting of genetic variants contributing to the sudden death of the young.
27435932
2016
rs3851101
SCN3B;LOC105369543
Schizoaffective disorder, bipolar type
G
0.700
GeneticVariation
GWASCAT
Genome-wide association study identifies 30 loci associated with bipolar disorder.
31043756
2019
rs375755770
×
Entrez Id:
55800
Gene Symbol:
SCN3B
SCN3B
Colorectal Carcinoma
0.700
GeneticVariation
UNIPROT
rs587777556
×
Entrez Id:
55800
Gene Symbol:
SCN3B
SCN3B
Brugada Syndrome 7
0.700
GeneticVariation
UNIPROT
Functional dominant-negative mutation of sodium channel subunit gene SCN3B associated with atrial fibrillation in a Chinese GeneID population.
20558140
2010
rs587777556
×
Entrez Id:
55800
Gene Symbol:
SCN3B
SCN3B
Brugada Syndrome 7
0.700
GeneticVariation
UNIPROT
Mutations in sodium channel β-subunit SCN3B are associated with early-onset lone atrial fibrillation.
21051419
2011
rs587777557
×
Entrez Id:
55800
Gene Symbol:
SCN3B
SCN3B
Brugada Syndrome 7
0.700
GeneticVariation
UNIPROT
Mutations in sodium channel β-subunit SCN3B are associated with early-onset lone atrial fibrillation.
21051419
2011
rs587777557
×
Entrez Id:
55800
Gene Symbol:
SCN3B
SCN3B
Brugada Syndrome 7
0.700
GeneticVariation
UNIPROT
Functional dominant-negative mutation of sodium channel subunit gene SCN3B associated with atrial fibrillation in a Chinese GeneID population.
20558140
2010
rs587777558
SCN3B;LOC105369543
Brugada Syndrome 7
0.700
GeneticVariation
UNIPROT
Functional dominant-negative mutation of sodium channel subunit gene SCN3B associated with atrial fibrillation in a Chinese GeneID population.
20558140
2010
rs587777558
SCN3B;LOC105369543
Brugada Syndrome 7
0.700
GeneticVariation
UNIPROT
Mutations in sodium channel β-subunit SCN3B are associated with early-onset lone atrial fibrillation.
21051419
2011