Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3851101
rs3851101
Entrez Id: 55800;105369543
Gene Symbol: SCN3B;LOC105369543
SCN3B;LOC105369543
CUI: C0270496
Disease:
Schizoaffective disorder, bipolar type 		G 0.700 GeneticVariation GWASCAT Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
dbSNP: rs147205617
rs147205617
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B
CUI: C1858430
Disease:
Death in infancy 		T 0.700 CausalMutation CLINVAR Postmortem genetic screening for the identification, verification, and reporting of genetic variants contributing to the sudden death of the young. 27435932 2016
dbSNP: rs879253730
rs879253730
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B
CUI: C0003811
Disease:
Cardiac Arrhythmia 		C 0.700 CausalMutation CLINVAR Postmortem genetic screening for the identification, verification, and reporting of genetic variants contributing to the sudden death of the young. 27435932 2016
dbSNP: rs879253730
rs879253730
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B
CUI: C0855329
Disease:
Electrocardiogram change 		C 0.700 CausalMutation CLINVAR Postmortem genetic screening for the identification, verification, and reporting of genetic variants contributing to the sudden death of the young. 27435932 2016
dbSNP: rs587777556
rs587777556
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B
CUI: C2751088
Disease:
Brugada Syndrome 7 		0.700 GeneticVariation UNIPROT Mutations in sodium channel β-subunit SCN3B are associated with early-onset lone atrial fibrillation. 21051419 2011
dbSNP: rs587777557
rs587777557
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B
CUI: C2751088
Disease:
Brugada Syndrome 7 		0.700 GeneticVariation UNIPROT Mutations in sodium channel β-subunit SCN3B are associated with early-onset lone atrial fibrillation. 21051419 2011
dbSNP: rs587777558
rs587777558
Entrez Id: 55800;105369543
Gene Symbol: SCN3B;LOC105369543
SCN3B;LOC105369543
CUI: C2751088
Disease:
Brugada Syndrome 7 		0.700 GeneticVariation UNIPROT Mutations in sodium channel β-subunit SCN3B are associated with early-onset lone atrial fibrillation. 21051419 2011
dbSNP: rs587777556
rs587777556
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B
CUI: C2751088
Disease:
Brugada Syndrome 7 		0.700 GeneticVariation UNIPROT Functional dominant-negative mutation of sodium channel subunit gene SCN3B associated with atrial fibrillation in a Chinese GeneID population. 20558140 2010
dbSNP: rs587777557
rs587777557
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B
CUI: C2751088
Disease:
Brugada Syndrome 7 		0.700 GeneticVariation UNIPROT Functional dominant-negative mutation of sodium channel subunit gene SCN3B associated with atrial fibrillation in a Chinese GeneID population. 20558140 2010
dbSNP: rs587777558
rs587777558
Entrez Id: 55800;105369543
Gene Symbol: SCN3B;LOC105369543
SCN3B;LOC105369543
CUI: C2751088
Disease:
Brugada Syndrome 7 		0.700 GeneticVariation UNIPROT Functional dominant-negative mutation of sodium channel subunit gene SCN3B associated with atrial fibrillation in a Chinese GeneID population. 20558140 2010
dbSNP: rs121918282
rs121918282
Entrez Id: 55800;105369543
Gene Symbol: SCN3B;LOC105369543
SCN3B;LOC105369543
CUI: C4013699
Disease:
ATRIAL FIBRILLATION, FAMILIAL, 16 		G 0.700 CausalMutation CLINVAR
dbSNP: rs121918282
rs121918282
Entrez Id: 55800;105369543
Gene Symbol: SCN3B;LOC105369543
SCN3B;LOC105369543
CUI: C2751088
Disease:
Brugada Syndrome 7 		G 0.700 GeneticVariation CLINVAR
dbSNP: rs121918282
rs121918282
Entrez Id: 55800;105369543
Gene Symbol: SCN3B;LOC105369543
SCN3B;LOC105369543
CUI: C2751088
Disease:
Brugada Syndrome 7 		G 0.700 CausalMutation CLINVAR
dbSNP: rs375755770
rs375755770
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B
CUI: C0009402
Disease:
Colorectal Carcinoma 		0.700 GeneticVariation UNIPROT
dbSNP: rs587777557
rs587777557
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B
CUI: C4013699
Disease:
ATRIAL FIBRILLATION, FAMILIAL, 16 		G 0.700 CausalMutation CLINVAR
dbSNP: rs587777558
rs587777558
Entrez Id: 55800;105369543
Gene Symbol: SCN3B;LOC105369543
SCN3B;LOC105369543
CUI: C4013699
Disease:
ATRIAL FIBRILLATION, FAMILIAL, 16 		T 0.700 CausalMutation CLINVAR
dbSNP: rs1783901
rs1783901
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B
CUI: C0042571
Disease:
Vertigo 		0.010 GeneticVariation BEFREE Our results suggest that the SNPs rs1939012 and rs1783901 may play a potential role of gene regulation and/or epistasis in a complex etiology of vertigo. 30300896 2018
dbSNP: rs1412069210
rs1412069210
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B
CUI: C0004238
Disease:
Atrial Fibrillation 		0.010 GeneticVariation BEFREE As a result, 2 novel heterozygous SCN4B mutations, p.V162G and p.I166L, were identified in 2 unrelated families with AF transmitted in an autosomal dominant pattern, respectively. 23604097 2013
dbSNP: rs147205617
rs147205617
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B
CUI: C1142166
Disease:
Brugada Syndrome (disorder) 		0.010 GeneticVariation BEFREE The Val110Ile mutation of SCN3B is a relatively common cause of SCN5A-negative BrS in Japan, which has a reduced sodium current because of the loss of cell surface expression of Nav1.5. 23257389 2013
dbSNP: rs587777556
rs587777556
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B
CUI: C0004238
Disease:
Atrial Fibrillation 		0.010 GeneticVariation BEFREE A novel A130V mutation was identified in a 46-year-old patient with lone AF, and the mutation was absent in 500 controls. 20558140 2010
dbSNP: rs121918282
rs121918282
Entrez Id: 55800;105369543
Gene Symbol: SCN3B;LOC105369543
SCN3B;LOC105369543
CUI: C1142166
Disease:
Brugada Syndrome (disorder) 		0.010 GeneticVariation BEFREE A missense mutation (L10P) was detected in exon 1 of SCN3B, the beta 3 subunit of the cardiac sodium channel, but not in any other gene known to be associated with Brugada syndrome or in 296 controls. 20031595 2009