PRKCI, protein kinase C iota, 5584

N. diseases: 78; N. variants: 3
Disease: Malignant neoplasm of prostate ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs546950
rs546950
Entrez Id: 5584
Gene Symbol: PRKCI
PRKCI
CUI: C0376358
Disease:
Malignant neoplasm of prostate 		0.020 GeneticVariation BEFREE In conclusion, the results revealed that PRKCI rs546950 variant decreased the risk of PCa in an Iranian population. 26475383 2015
dbSNP: rs546950
rs546950
Entrez Id: 5584
Gene Symbol: PRKCI
PRKCI
CUI: C0376358
Disease:
Malignant neoplasm of prostate 		0.020 GeneticVariation BEFREE In the joint analysis of first and second phase two SNPs of the PRKCI gene showed an association with risk of prostate cancer (OR(allele) = 0.85, 95% CI 0.78-0.94, p = 1.3 x 10⁻³ for rs546950 and OR(allele) = 0.84, 95% CI 0.76-0.93, p = 5.6 x 10⁻⁴ for rs4955720). 21373201 2011