PRKCI, protein kinase C iota, 5584

N. diseases: 78; N. variants: 3
Disease: Prostate carcinoma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs71277158
rs71277158
Entrez Id: 5584
Gene Symbol: PRKCI
PRKCI
CUI: C0600139
Disease:
Prostate carcinoma 		T 0.700 GeneticVariation GWASCAT Two susceptibility loci identified for prostate cancer aggressiveness. 25939597 2015
dbSNP: rs546950
rs546950
Entrez Id: 5584
Gene Symbol: PRKCI
PRKCI
CUI: C0600139
Disease:
Prostate carcinoma 		0.020 GeneticVariation BEFREE In conclusion, the results revealed that PRKCI rs546950 variant decreased the risk of PCa in an Iranian population. 26475383 2015
dbSNP: rs546950
rs546950
Entrez Id: 5584
Gene Symbol: PRKCI
PRKCI
CUI: C0600139
Disease:
Prostate carcinoma 		0.020 GeneticVariation BEFREE In the joint analysis of first and second phase two SNPs of the PRKCI gene showed an association with risk of prostate cancer (OR(allele) = 0.85, 95% CI 0.78-0.94, p = 1.3 x 10⁻³ for rs546950 and OR(allele) = 0.84, 95% CI 0.76-0.93, p = 5.6 x 10⁻⁴ for rs4955720). 21373201 2011