RELN, reelin, 5649

N. diseases: 178; N. variants: 52
Disease: Alzheimer's Disease ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs528528
rs528528
Entrez Id: 5649
Gene Symbol: RELN
RELN
CUI: C0002395
Disease:
Alzheimer's Disease 		0.020 GeneticVariation BEFREE A significant association between the genotypes RELN (rs528528 and rs2299356), PLK2 (rs15009 and rs702723), and CAMK2A (rs3756577 and rs3822606) and AD or MCI was found. 24384746 2016
dbSNP: rs528528
rs528528
Entrez Id: 5649
Gene Symbol: RELN
RELN
CUI: C0002395
Disease:
Alzheimer's Disease 		0.020 GeneticVariation BEFREE Among men, but not in women the rs528528 T/T and rs607755 A/A genotypes were significantly associated with the susceptibility to AD. 26384575 2015
dbSNP: rs607755
rs607755
Entrez Id: 5649
Gene Symbol: RELN
RELN
CUI: C0002395
Disease:
Alzheimer's Disease 		0.020 GeneticVariation BEFREE Among men, but not in women the rs528528 T/T and rs607755 A/A genotypes were significantly associated with the susceptibility to AD. 26384575 2015
dbSNP: rs607755
rs607755
Entrez Id: 5649
Gene Symbol: RELN
RELN
CUI: C0002395
Disease:
Alzheimer's Disease 		0.020 GeneticVariation BEFREE To explore the potential contribution of RELN gene variants in the pathogenesis of AD, we investigated three polymorphisms spanning the RELN locus, i.e., a triplet tandem repeat in the 5'UTR and two single-nucleotide polymorphisms (SNPs) rs607755 and rs2229874, located in the splice-junction of exon 6 and in the coding region of exon 50. 18599960 2008
dbSNP: rs2299356
rs2299356
Entrez Id: 5649
Gene Symbol: RELN
RELN
CUI: C0002395
Disease:
Alzheimer's Disease 		0.010 GeneticVariation BEFREE A significant association between the genotypes RELN (rs528528 and rs2299356), PLK2 (rs15009 and rs702723), and CAMK2A (rs3756577 and rs3822606) and AD or MCI was found. 24384746 2016