HTRA1, HtrA serine peptidase 1, 5654

N. diseases: 164; N. variants: 45
Disease: Vision Impairment and Blindness ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1049331
rs1049331
Entrez Id: 5654;105378525
Gene Symbol: HTRA1;LOC105378525
HTRA1;LOC105378525
CUI: C1456582
Disease:
Vision Impairment and Blindness 		0.010 GeneticVariation BEFREE In age-related macular degeneration (AMD), a common cause of vision impairment and blindness in industrialized societies, two synonymous polymorphisms (rs1049331:C>T, and rs2293870:G>T) in exon 1 of the HTRA1 gene were associated with a high risk to develop disease. 26310622 2015