PAK5, p21 (RAC1) activated kinase 5, 57144

N. diseases: 52; N. variants: 6
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs221013
rs221013
Entrez Id: 57144
Gene Symbol: PAK5
PAK5
CUI: C0596887
Disease:
mathematical ability 		T 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs2224610
rs2224610
Entrez Id: 57144
Gene Symbol: PAK5
PAK5
CUI: C1519383
Disease:
Smoking Behaviors 		0.700 GeneticVariation GWASCAT Mercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer. 26053186 2015
dbSNP: rs2224610
rs2224610
Entrez Id: 57144
Gene Symbol: PAK5
PAK5
CUI: C0037369
Disease:
Smoking 		0.700 GeneticVariation GWASCAT Mercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer. 26053186 2015
dbSNP: rs6056869
rs6056869
Entrez Id: 57144
Gene Symbol: PAK5
PAK5
CUI: C0033860
Disease:
Psoriasis 		A 0.700 GeneticVariation GWASCAT Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility. 25903422 2015
dbSNP: rs1484691555
rs1484691555
Entrez Id: 57144
Gene Symbol: PAK5
PAK5
CUI: C0278883
Disease:
Metastatic melanoma 		0.700 GeneticVariation UNIPROT
dbSNP: rs952665081
rs952665081
Entrez Id: 57144;105372523
Gene Symbol: PAK5;LOC105372523
PAK5;LOC105372523
CUI: C1319315
Disease:
Adenocarcinoma of large intestine 		0.700 GeneticVariation UNIPROT
dbSNP: rs6056923
rs6056923
Entrez Id: 57144
Gene Symbol: PAK5
PAK5
CUI: C0024143
Disease:
Lupus Nephritis 		0.010 GeneticVariation BEFREE Four trans-eSNPs were observed to be associated with susceptibility to LN (P < 0.05), including ANKRD50 rs17008504, AGA rs2271100, PAK7 rs6056923, and TET2 rs1391441, while seven other trans-eSNPs showed marginal significant associations (0.05 < P < 0.1). 26509176 2015