PTGS2, prostaglandin-endoperoxide synthase 2, 5743

N. diseases: 1234; N. variants: 27
Disease: Neoplasms ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs689466
rs689466
Entrez Id: 5743;103752588
Gene Symbol: PTGS2;PACERR
PTGS2;PACERR
CUI: C0027651
Disease:
Neoplasms 		0.010 GeneticVariation BEFREE Likewise, the haplotype *4, which contains variant rs689466, was associated with shorter disease-free survival among obese patients (HR<sub>adj</sub> = 3.3; 95% CI = 1.8-6.0), either in luminal (HR<sub>adj</sub> = 3.5; 95% CI = 1.6-7.3) or HER2-like and triple-negative (HR<sub>adj</sub> = 3.1; 95% CI = 1.1-8.9) tumors. 29321183 2018
dbSNP: rs5273
rs5273
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0027651
Disease:
Neoplasms 		0.010 GeneticVariation BEFREE Prostaglandin H synthase 2 variant (Val511Ala) in African Americans may reduce the risk for colorectal neoplasia. 12433707 2002