LRRC7, leucine rich repeat containing 7, 57554

N. diseases: 26; N. variants: 6
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12062605
rs12062605
Entrez Id: 57554
Gene Symbol: LRRC7
LRRC7
CUI: C0410702
Disease:
Adolescent idiopathic scoliosis 		0.700 GeneticVariation GWASCAT The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease. 30019117 2018
dbSNP: rs12062605
rs12062605
Entrez Id: 57554
Gene Symbol: LRRC7
LRRC7
CUI: C1837461
Disease:
SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3 		0.700 GeneticVariation GWASCAT The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease. 30019117 2018
dbSNP: rs1418004
rs1418004
Entrez Id: 57554
Gene Symbol: LRRC7
LRRC7
CUI: C0596887
Disease:
mathematical ability 		T 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs687531
rs687531
Entrez Id: 57554
Gene Symbol: LRRC7
LRRC7
CUI: C0596887
Disease:
mathematical ability 		T 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs2226284
rs2226284
Entrez Id: 57554
Gene Symbol: LRRC7
LRRC7
CUI: C0020538
Disease:
Hypertensive disease 		0.700 GeneticVariation GWASCAT Genetic association of short sleep duration with hypertension incidence--a 6-year follow-up in the Korean genome and epidemiology study. 22322875 2012
dbSNP: rs17131023
rs17131023
Entrez Id: 57554
Gene Symbol: LRRC7
LRRC7
CUI: C0027404
Disease:
Narcolepsy 		0.700 GeneticVariation GWASDB Genome-wide association database developed in the Japanese Integrated Database Project. 19629137 2009
dbSNP: rs672961
rs672961
Entrez Id: 57554
Gene Symbol: LRRC7
LRRC7
CUI: C0035222
Disease:
Respiratory Distress Syndrome, Adult 		0.010 GeneticVariation BEFREE One of those SNPs (rs672961) was previously associated with trauma-induced ARDS and modified the promoter activity of the NFE2L2 gene, showing an odds ratio of 1.93 per T allele (95 % confidence interval, 1.17-3.18; p = 0.0089). 26077880 2015