BCL2, BCL2 apoptosis regulator, 596

N. diseases: 1456; N. variants: 27
Disease: Neoplasms ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2279115
rs2279115
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0027651
Disease:
Neoplasms 		0.010 GeneticVariation BEFREE Considering these promising results, rs2279115 may be a tumor marker for cancertherapy in Asia. 28445963 2017
dbSNP: rs1564483
rs1564483
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0027651
Disease:
Neoplasms 		0.010 GeneticVariation BEFREE For BCL2, minor allele carriers of rs1564483 were more likely to have hormone receptor-positive tumours than the major homozygotes. 22037783 2012
dbSNP: rs4987852
rs4987852
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0027651
Disease:
Neoplasms 		0.010 GeneticVariation BEFREE Another SNP in BCL2, rs4987852, was associated with tumour stages II-IV and histologic grade 3. 22037783 2012
dbSNP: rs747504890
rs747504890
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0027651
Disease:
Neoplasms 		0.010 GeneticVariation BEFREE G129R-endostatin has a significantly prolonged serum half-life as compared with that of G129R or endostatin alone, and exhibited greater tumor inhibitory effects than G129R and endostatin individually or in combination. 12839947 2003